Cardiomyopathy Trial, Recruiting NCT06688396 Sponsor: Lancaster General Hospital Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT06688396
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For the main patient (called the "Proband"):

  • You are 18 years of age or older
  • A doctor has confirmed you have a specific type of heart condition called non-ischemic dilated cardiomyopathy (a weakened, enlarged heart not caused by blocked arteries), where your heart's pumping function measured at 45% or below at some point in your care
  • You have at least one living adult close family member (parent, child, or sibling) who could also participate
  • You are able to give your agreement to take part in the study

For close family members (called "First-Degree Relatives" or FDRs):

  • You are 18 years of age or older and are a parent, child, or sibling of the main patient
  • The main patient has already agreed to take part in the study
  • You are able to give your verbal agreement to participate
  • You have access to a smartphone or tablet with mobile data or Wi-Fi

Who may not be able to join:

For the main patient:

  • Your heart condition is caused by something other than non-ischemic dilated cardiomyopathy, as judged by the study doctor
  • You have already told your close family members to get their hearts checked
  • Your weakened heart is due to blocked or narrowed arteries, a past heart attack, or certain test results suggesting reduced blood flow to the heart
  • You have a moderate or severe heart valve problem that is not related to your heart muscle condition
  • You were born with a structural heart defect
  • You have severe high blood pressure that is not being treated or cannot be treated
  • Your heart condition is caused by a temporary or reversible issue, such as an abnormal heart rhythm, a thyroid problem, or iron build-up in the body
  • Your reduced heart function is linked to other causes such as pregnancy, heart inflammation, certain diseases (e.g., amyloidosis or sarcoidosis), alcohol, drug use, or chemotherapy
  • (For certain study locations only) You live too far away to travel to the study site

For close family members:

  • You have already been told to get cardiac screening or have already had a heart ultrasound (echocardiogram) for screening purposes
  • You have already been diagnosed with a reduced heart pumping function
  • (For certain study locations only) You live too far away to travel to the study site

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Roy Small, MD, Penn Medicine / Lancaster General Hospital

Phone: 717-544-1777

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Lancaster General Hospital
Registry
ClinicalTrials.gov
Start date
4 December 2024
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

This study's primary endpoint is to assess the feasibility of performing AI-EKG test and the subsequent uptake of cardiac screening in FDR of DCM patients.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov