Phase 2 Liver Cancer Trial, Recruiting NCT06690528 Sponsor: Azienda Ospedaliera di Padova Condition: Liver Cancer
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Phase 2 Liver Cancer Trial, Recruiting

NCT06690528
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults who were between 18 and 75 years old when they were diagnosed
  • People who have been confirmed by laboratory testing (from a tissue or cell sample) to have pancreatic adenocarcinoma (a specific type of pancreatic cancer) that was considered removable by surgery or borderline removable at the time of diagnosis
  • People who, at diagnosis, had a limited number of cancer spots on the liver only — specifically up to 3 spots visible on scans — with no cancer spread to other areas of the body
  • People who are in reasonably good general health and able to carry out daily activities (confirm with trial site regarding the specific fitness scale used)
  • People whose cancer showed a partial response or was stable after completing their first course of chemotherapy, as measured by standard scan-based guidelines
  • People whose blood levels of a cancer marker called CA19-9 stayed the same or went down (or rose by no more than 20%) after chemotherapy
  • People whose liver spots are considered removable by surgery, or small enough (no larger than 20mm) to potentially be treated with a needle-based heat treatment

Who may not be able to join:

  • People whose pancreatic cancer has grown in a way that blocks it from being surgically removed, based on standard cancer guidelines
  • People whose liver disease is considered too extensive to be removed, as decided by a team of specialists
  • People whose cancer has spread to organs other than the liver
  • People who have serious other health conditions that would make surgery too risky
  • People who are pregnant
  • People who have a medical reason why surgery would not be safe for them
  • People who have already had surgery to remove the primary pancreatic tumour or any liver spots
  • People who have cancer that has spread beyond the liver
  • People who are unable to give informed consent or to attend follow-up appointments
  • People whose cancer progressed (grew or spread) after chemotherapy, based on standard scan measurements
  • People whose CA19-9 blood marker levels rose by more than 20% after chemotherapy

Note: Individual trial sites may apply additional exclusion criteria based on their own guidelines.


Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Giovanni Marchegiani, MD, PhD, Professor, University of Padova

Phone: +390498212259

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Azienda Ospedaliera di Padova
Registry
ClinicalTrials.gov
Start date
6 November 2024
Est. completion
1 November 2028

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Two-year OS (2y-OS) rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov