Phase 2 Breast Cancer Trial, Not Yet Recruiting NCT06691594 Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Not Yet Recruiting

NCT06691594
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have given signed written consent before enrolling
  • People aged 18 years or older
  • People with a good general health and activity level (ECOG performance score of 0 or 1, meaning fully active or able to carry out light work)
  • People newly diagnosed with a specific stage of breast cancer (T1c N1-2 or T2-3 N0-2 — confirm exact staging details with the trial site)
  • People whose breast cancer is "triple-negative" and has a PD-L1 CPS score below 10 (a specific laboratory marker measured from the tumour)
  • People whose blood counts meet certain minimum levels — including haemoglobin, white blood cells (neutrophils), and platelets
  • People whose kidney function blood tests are within an acceptable range (BUN and creatinine no more than 1.5 times the upper limit of normal)
  • People whose liver function blood tests are within an acceptable range (bilirubin, ALP, AST, and ALT at acceptable levels)
  • Women who could become pregnant and are willing to use contraception throughout the study
  • Women who have had a negative pregnancy test (blood or urine) within 7 days before starting treatment

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People with occult breast cancer (cancer that cannot be detected in the breast itself)
  • People with cancer in both breasts
  • People whose breast tumour is not suitable for a type of targeted radiation therapy called SBRT (confirm with trial site)
  • People who are unable to have an MRI scan
  • People with a history of another cancer that may affect their survival
  • People with an active autoimmune disease, or a history of autoimmune disease
  • People currently using immune-suppressing medications or systemic steroids within the 2 weeks before enrolling
  • People with a known allergy to any ingredient in the study drugs
  • People with serious heart symptoms or heart conditions that are not well controlled
  • People with an active infection, or an unexplained fever above 38.5°C at the time of screening or before the first dose
  • People with other factors that could cause them to leave the study early, such as serious ongoing illnesses, significantly abnormal lab results, or personal or family circumstances that could affect safety or data collection

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026

Contact this trial

Phone: 13661135602

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Registry
ClinicalTrials.gov
Start date
1 February 2025
Est. completion
1 November 2028

Primary endpoints

the efficacy of neoadjuvant SBRT combined with PD-1 monoclonal antibody and chemotherapy

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov