Cardiomyopathy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older, of any sex.
• People who have been diagnosed with heart failure caused by a condition called non-ischemic dilated cardiomyopathy (a type of weakened, enlarged heart not caused by blocked arteries), with or without a known genetic cause.
• People whose heart pumping function, as measured by a cardiac MRI scan, shows the heart is pumping at 49% or less of its normal capacity.
• People who have been on a stable, optimised heart failure medication plan for at least 3 months before joining the trial.
• People who have given their informed consent to participate.

Who may not be able to join:

• People who have previously been diagnosed with heart failure caused by blocked heart arteries (ischemic dilated cardiomyopathy).
• People who have a prior diagnosis of established cardiovascular disease related to fatty buildup in the arteries, such as chest pain (angina), heart attack, mini-stroke or stroke, or poor blood flow to the legs or other areas of the body.
• People whose heart failure medications have been changed in the last 3 months.
• People who have had a worsening of their heart failure in the past 3 months, including a hospital stay for heart failure or the need for intravenous fluid or heart-support treatments given in a clinic.
• People with poorly controlled cholesterol or triglyceride (blood fat) levels that remain above certain thresholds despite treatment.
• People who cannot safely have a cardiac MRI scan — for example, due to severe claustrophobia (fear of enclosed spaces), or because they have a medical device in their body that is not safe in MRI environments, such as a pacemaker, an implanted heart defibrillator, or a cardiac resynchronisation device.
• People who have a diagnosed liver or bile duct condition, including non-alcoholic fatty liver disease or gallstones that have not been surgically treated.
• People who have a history of acute or chronic pancreatitis (inflammation of the pancreas).
• People with a known allergy to fish or nuts.
• People whose life expectancy is estimated to be less than 12 months.
• People who are pregnant, or planning to become pregnant in the next 4 months.
• People who are currently breastfeeding.
• People who are already taking part in another randomised clinical trial.
• People who are unable to give consent or to attend the required follow-up visits for the study.

Important: Always verify eligibility with the trial site directly before applying.