Phase 3 Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 or older who are in hospital for acute heart failure with fluid buildup (congestion), shown by at least 2 signs such as swollen legs, fluid in the abdomen, shortness of breath when lying down, sudden breathlessness at night, recent weight gain of around 5 pounds, or fluid seen on a chest X-ray or ultrasound — or, if a special heart pressure monitoring line is in place, a high pressure reading plus at least one of those physical signs
- People enrolled into the trial within 24 hours of being admitted to hospital for acute heart failure
- People for whom doctors plan to use intravenous (IV) water-removing medication (loop diuretics) during the hospital stay
- People whose kidneys are functioning at a level of at least 30 ml/min/1.73m² as measured by a standard medical calculation (confirm with trial site)
Who may not be able to join:
- People who are unable to follow instructions
- People who have been treated with a specific type of diuretic medication that works on the proximal tubule of the kidney (confirm with trial site for specific medicines)
- People whose top blood pressure number (systolic) is below 90 mmHg
- People whose kidney function is measured at less than 20 ml/1.73m² by a standard medical calculation
- People with Type 1 diabetes
- People whose breathing difficulties are mainly caused by something other than a heart condition
- People in cardiogenic shock (when the heart is suddenly unable to pump enough blood)
- People who have had an acute coronary syndrome (such as a heart attack or unstable chest pain) within the 30 days before enrolment
- People who have had or are planned to have a heart procedure (such as a stent or bypass surgery) within 30 days before enrolment
- People showing signs of a dangerous chemical imbalance related to diabetes, such as ketoacidosis or high blood sugar with certain blood test results (confirm with trial site)
- People who are pregnant or currently breastfeeding
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Noha Mansour, PhD, Department of Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy, University of Mansoura
Phone: +201009648197
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in dyspnea VAS (Visual analogue scale)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.