Breast Cancer Trial, Not Yet Recruiting NCT06786585 Sponsor: Eastern Cooperative Oncology Group Condition: Breast Cancer
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Breast Cancer Trial, Not Yet Recruiting

NCT06786585
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Patients must fit into one of three groups (cohorts) described below.
  • Cohort 1: People who previously took part in the TAILORx study, received a recurrence score (a lab test result) anywhere between 0 and 100, and have since had a biopsy confirming that their cancer came back — either in the same area, in a distant part of the body, or both.
  • Cohort 2: People who previously took part in Step 2 of the RxPONDER study, received a recurrence score between 0 and 25, and have since had a biopsy confirming that their cancer came back — either in the same area, in a distant part of the body, or both.
  • Cohort 3: People who previously took part in Step 1 of the RxPONDER study and were found to have a high Oncotype DX recurrence score between 26 and 100.
  • People who are able to understand and willing to sign a written consent form to take part in this observational (non-treatment) study; people who cannot make this decision independently but have a legally authorised representative, caregiver, or family member available may also be considered eligible.
  • People in Cohorts 1 and 2 must have a tumour tissue sample from when their cancer came back, available at the time of joining, to be sent to the study's central facility within 30 days of registration.
  • People in Cohort 3 must have a tumour tissue sample from their original (primary) tumour available at the time of joining, to be sent to the study's central facility within 30 days of registration.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • No exclusion criteria were listed in the source information (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 29 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Joseph A Sparano, MD, Eastern Cooperative Oncology Group

Phone: 212-659-6754

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Eastern Cooperative Oncology Group
Registry
ClinicalTrials.gov
Start date
1 June 2025
Est. completion
1 April 2027

Primary endpoints

Patterns of clonal evolution; Prevalence of the integrative cluster (IntClust) and intrinsic (PAM50) subtypes; Molecular signatures of primary tumor specimens

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 29 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov