Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
For people with ischemic heart disease (heart disease caused by blocked arteries):
- Adults between 18 and 80 years old (male or female)
- People who have been scheduled for coronary artery bypass graft (CABG) heart surgery as part of their regular medical care
- People who have one or more narrowed or blocked coronary arteries (the blood vessels that supply the heart)
- People whose heart pumping strength is 40% or less, or who have been referred for a heart viability assessment
- People who are able to follow the preparation steps for the imaging scans, such as fasting and managing blood sugar levels before the scan
- Current medications taken within 24 hours of the scan are permitted and will be recorded
- Females of childbearing age who have a negative pregnancy test on the day of scanning
- People with no known reasons they cannot safely have a 3T MRI, a SPECT scan, or an FDG PET scan
For healthy volunteers:
- Adults between 18 and 80 years old (male or female)
- People with no history of coronary artery disease or diabetes
- People who are medically suitable for a 3T MRI, SPECT scan, and FDG PET scan
- Females of childbearing age who have a negative pregnancy test on the day of scanning
Who may not be able to join:
For people with ischemic heart disease:
- People younger than 18 or older than 80 years of age
- People who are not scheduled for CABG surgery, or who do not have a confirmed diagnosis of coronary artery disease
- People with a history of a heart attack that left more than 50% of the heart wall permanently scarred (based on prior imaging or medical history)
- People who cannot safely undergo a 3T MRI (for example, due to a pacemaker, defibrillator, or metal implants), a SPECT scan (for example, due to significant irregular heartbeat or unstable blood pressure), or an FDG PET scan (for example, due to severely impaired blood sugar processing)
- Females who have a positive pregnancy test or who are currently breastfeeding on the day of scanning
- People with severely reduced kidney function (confirm with trial site)
- People with poorly controlled diabetes, specifically a long-term blood sugar level (HbA1c) above 9%, or those who are unable to reach stable blood sugar levels before the scan
For healthy volunteers:
- People with a history of coronary artery disease, diabetes, or other medical conditions that the study team determines would make participation unsuitable
- Females who have a positive pregnancy test or who are currently breastfeeding on the day of scanning
- People with reasons they cannot safely have an MRI (such as metal implants or claustrophobia), a SPECT scan, or an FDG PET scan
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Gaurav Sharma, PhD, MBA, University of Texas Southwestern Medical Center
Phone: 214-645-7700
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Assessment of Myocardial Metabolism and Viability via HP-13C MRI, FDG-PET, and SPECT MPI
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.