Sleep Disorders Trial, Recruiting NCT06824415 Sponsor: Stanford University Condition: Sleep Disorders
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Sleep Disorders Trial, Recruiting

NCT06824415
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 65 years old
  • People who have been diagnosed with Major Depressive Disorder (a medical diagnosis of serious, ongoing depression)
  • People whose depression is currently rated as moderate to severe
  • People who have tried at least one antidepressant medication in the past that did not work well enough
  • People who have been on a stable, unchanged antidepressant dose for at least 6 weeks before joining the trial
  • Healthy volunteers between 18 and 65 years old who do not have depression symptoms, are not taking antidepressants or antipsychotic medications, and do not have major psychiatric, neurological, substance use, or other conditions affecting brain function, may also be eligible to participate as a comparison group (confirm with trial site)

Who may not be able to join:

  • People with an intellectual disability
  • People with a significant head injury or a neurological disorder (a condition affecting the brain or nervous system)
  • People who are pregnant or in the postpartum period (recently given birth)
  • People who have any medical reasons that make TMS (a type of brain stimulation) or MRI (a type of brain scan) unsafe for them — for example, certain metal implants
  • People who are currently experiencing active substance use issues or thoughts of suicide

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Umair Hassan, PhD, Stanford University

Phone: 408-909-2203

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 May 2025
Est. completion
30 May 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Baseline TMS-EEG after iTBS; Change in Baseline TMS-EEG after NREM Sleep; Change in N-back Accuracy Performance; Change in N-back Reaction Time Performance; Change in MSIT Accuracy Performance; Change in MSIT Reaction Time Performance

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov