Breast Cancer Trial, Not Yet Recruiting NCT06825975 Sponsor: Guangdong Provincial People's Hospital Condition: Breast Cancer
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Breast Cancer Trial, Not Yet Recruiting

NCT06825975
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who understand the study process, are willing to take part voluntarily, and are able to sign a consent form.
  • Women aged 18 to 60 years old who have been diagnosed with primary invasive breast cancer in one breast only, confirmed by a tissue sample (biopsy), not including certain rare types such as occult, inflammatory, or eczema-like breast cancer.
  • People whose cancer meets the specific size, stage, or type criteria that doctors use to decide whether pre-surgery treatment (called neoadjuvant therapy) is appropriate — this includes certain locally advanced cancers, cancers where breast-conserving or lymph-node-sparing surgery is not yet possible, certain HER2-positive or triple-negative breast cancers with positive lymph nodes, or tumours 2cm or larger (confirm with trial site).
  • People with a general health and activity level rated as 0 or 1 on a standard medical scale, meaning they are fully active or have only minor limitations in physical activity.
  • People whose heart pumping function (measured as LVEF) is at or above 55%.
  • People whose blood test results show adequate bone marrow function, including sufficient white blood cells, neutrophils, platelets, and haemoglobin levels.
  • People whose liver and kidney function blood tests are within acceptable ranges as defined by the trial.
  • Women who have not gone through menopause and have not had surgical sterilisation must agree to use contraception throughout treatment and for at least 7 months after the last dose of the study treatment.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have a medical reason they cannot receive hyperbaric oxygen therapy, including: an untreated collapsed lung (pneumothorax); currently taking a medication called disulfiram; currently taking certain cancer medicines including bleomycin, cisplatin, or adriamycin; certain lung conditions such as severe chronic obstructive pulmonary disease, herpetic lung disease, active lung infections, or uncontrolled asthma; a history of middle ear surgery; middle ear problems such as eustachian tube dysfunction or recurring dizziness (vertigo); or an eye condition called retinal detachment.
  • People who have previously received hyperbaric oxygen therapy.
  • People whose cancer has spread to distant parts of the body, including lymph nodes in the opposite breast or the area between the lungs (mediastinum).
  • People who have had another cancer in the past two years, with the exception of certain fully treated skin cancers or early-stage cervical cancer.
  • People who are pregnant or breastfeeding.
  • People with uncontrolled high blood pressure, or serious heart, liver, kidney, or other medical or psychiatric conditions.
  • People who had a major surgical procedure unrelated to breast cancer within the 4 weeks before joining the trial, or who have not fully recovered from such a procedure.
  • People with serious or uncontrolled infections that could interfere with the study, including active hepatitis, HIV-positive status, or lung infections.
  • People with a recent history of blood clots (thromboembolism) who are taking full-dose blood-thinning medication.
  • People who have any other condition that the trial doctor considers would make participation in the study unsuitable.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 86+13829694500

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Guangdong Provincial People's Hospital
Registry
ClinicalTrials.gov
Start date
12 February 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

pCR rate after hyperbaric oxygen combined with neoadjuvant therapy in breast cancer patients

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov