Depression and Anxiety Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults between 18 and 60 years old (any gender).
- People who have been diagnosed with major depressive disorder according to the DSM-5 diagnostic guidelines.
- People whose depression has been rated as moderate to severe or above on a standard 17-item depression scale (a score of 18 or higher on the HAMD-17).
- People whose current medication or talking therapy has remained unchanged for at least 4 weeks before the study begins.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People with a history of serious physical illness or conditions that may affect the brain or nervous system (for example, tumours or syphilis).
- People with neurological conditions or an increased risk of seizures, such as a history of head injury, skull abnormalities, heavy alcohol use, abnormal brain wave test results, brain structure abnormalities seen on an MRI scan, or a family history of epilepsy.
- People whose depression is linked to bipolar disorder or to another psychiatric condition (for example, depression related to substance use).
- People who cannot safely have an MRI scan or transcranial magnetic stimulation (a type of brain stimulation therapy), such as those who have metal implants or electronic devices in their body (including metal in the skull, cochlear implants, pacemakers, or stents), or those who experience severe claustrophobia.
- People who have psychotic symptoms that require treatment with antipsychotic medication alongside other treatments.
- People considered to be at high risk of suicide, or who have recently attempted suicide or seriously harmed themselves in a way that requires urgent medical attention.
- People who are pregnant, breastfeeding, or planning to become pregnant during the trial period.
- People whom the trial investigators consider unsuitable for participation for any other reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Principal Investigator: Huaning Wang, Xijing Hospital
Phone: 18294037117
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.
Where this trial is recruiting
Primary endpoints
Change in Montgomery-Asberg Depression Rating Scale (MADRS) scores from baseline to treatment day 10
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.