Rheumatoid Arthritis Trial, Recruiting NCT06841562 Sponsor: Duke University Condition: Rheumatoid Arthritis
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Rheumatoid Arthritis Trial, Recruiting

NCT06841562
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with rheumatoid arthritis (RA) within the last 6 months and are not currently taking biologic (advanced injection or infusion) RA medications, though you may be taking one or more standard RA pills such as hydroxychloroquine, methotrexate, sulfasalazine, leflunomide, or azathioprine.
  • Your blood tests show certain markers linked to RA (rheumatoid factor or anti-CCP antibodies), or your X-rays show joint damage typical of RA.
  • You have been diagnosed with RA based on recognised international guidelines (confirm with trial site).
  • Your RA is currently active — meaning it is not fully under control or in remission based on a standard disease activity score.
  • You have been on stable doses of all your RA and heart/cardiovascular medications for at least 1 month (except for steroid medications).

Who may not be able to join:

  • You are pregnant or planning to become pregnant during the study period.
  • You are currently taking insulin injections.
  • You have another type of joint or muscle disease, or certain other specific medical conditions affecting the joints or metabolism (confirm with trial site for the full list).
  • You currently have cancer, other than certain very minor skin cancers treated with simple procedures.
  • You have a serious heart or circulation condition that would make exercise testing unsafe, such as unstable chest pain, uncontrolled heart rhythm problems, active heart infection, severe heart valve problems, heart failure, a recent blood clot in the lungs or legs, heart muscle inflammation, or a physical disability preventing safe exercise testing.
  • You have certain heart or circulation conditions that may make exercise testing risky, such as significant blockages in heart arteries, uncontrolled fast heart rate, recent stroke or mini-stroke, a heart muscle condition causing obstruction, or other uncontrolled health problems like very high blood pressure, severe anaemia, or an overactive thyroid (confirm with trial site).
  • You had a heart attack within the last 6 months.
  • Your resting blood pressure is very high (at or above 180/110 mmHg).
  • You do not have access to the internet.
  • You are planning to deliberately try to lose weight during the study.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Brian J Andonian, MD, MHSc, Duke University

Phone: 19196606766

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
14 July 2025
Est. completion
31 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Feasibility of exercise training intervention

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov