HIV and AIDS Trial, Recruiting NCT06845046 Sponsor: VA Office of Research and Development Condition: HIV and AIDS
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HIV and AIDS Trial, Recruiting

NCT06845046
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have served in the military as a veteran
  • People who are living with HIV
  • People whose HIV treatment uses a specific type of medication called an integrase strand transfer inhibitor, taken for at least 3 months
  • People whose HIV viral load is undetectable (less than 50 copies/ml — meaning the virus is well controlled)
  • People aged 20 years or older
  • People with a body mass index (BMI) between 28 and 50 kg/m²

Who may not be able to join:

  • People whose body weight has changed by more than 5% (gained or lost) in the past 3 months
  • People who have been diagnosed with a mitochondrial disorder (a condition affecting how cells produce energy)
  • People who have been diagnosed with type 1 or type 2 diabetes
  • People who are taking metformin or other diabetes-related medications for pre-diabetes
  • People whose HbA1c blood sugar level was above 6.5% at the screening visit (a measure of average blood sugar over time)
  • People who have ongoing inflammatory conditions or who regularly use corticosteroid medications
  • People with stage 3 or more advanced kidney disease
  • People who are taking dietary or herbal supplements known to affect body weight, muscle mass, or immune function
  • People who are unable to have an MRI scan for any reason
  • People who are unable to complete physical fitness tests due to physical or anatomical limitations
  • People for whom an exercise stress test (called a CPET) would be unsafe — for example, due to exercise-induced heart problems or a need for supplemental oxygen

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Heidi J Silver, PhD, Tennessee Valley Healthcare System Nashville Campus, Nashville, TN

Phone: (615) 875-9355

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
15 July 2025
Est. completion
30 March 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Myosteatosis; MixedMeal GTT; Physical Function

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov