Phase 4 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older
- People who are scheduled for a major non-heart surgery lasting at least 60 minutes under general anaesthesia, with the surgery expected to finish by 6:00 pm
- People who are planned to use a self-controlled pain relief drip (where the patient can press a button to release pain medication) after their surgery
Who may not be able to join:
- People having emergency surgery, bladder/urethra surgery, or an organ transplant
- People who are pregnant or breastfeeding
- People who were already taking sleeping tablets for sleep problems or antidepressants for depression before surgery
- People with a history of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis (a muscle weakness condition)
- People who are unable to communicate due to coma, severe dementia, speech disorders, past brain injury from lack of oxygen, traumatic brain injury, or previous brain surgery
- People with an overactive thyroid or a type of adrenal gland tumour called pheochromocytoma
- People with certain serious heart conditions before surgery, including very poor heart pumping function, abnormal heart rhythm conditions, a slow heart rate below 50 beats per minute, certain heart electrical blockages without a pacemaker, or very low blood pressure even with medication to raise it
- People diagnosed with sleep apnoea, or those assessed as being at moderate-to-high risk of sleep apnoea based on a screening tool called STOP-Bang
- People with severe liver disease, severe kidney disease requiring dialysis, or those whose overall health is rated as very poor under standard medical classification (ASA class IV or higher)
- People with a known allergy or sensitivity to either of the study medications (dexmedetomidine or esketamine)
- People with any other condition the trial team considers unsuitable for participation (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Dong-Xin Wang, Dong-Xin Wang, MD, PhD, Peking University First Hospital
Phone: +86 19801260665
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence of sleep disturbances within 3 days after surgery
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.