Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People with end-stage kidney failure who are currently on peritoneal dialysis (a type of home dialysis that uses the abdomen) with a working dialysis catheter
- People whose top blood pressure reading is above 130 mmHg
- People whose blood sodium level is above 135 mmol/L (based on a blood test)
- People who produce less than 400ml of urine per day
- People who have been on the same peritoneal dialysis routine for at least 2 months, without needing the strongest glucose dialysis solution available
- People who have been on peritoneal dialysis for at least 6 months
- People who are considered to be at a stable, healthy fluid balance (at their "dry weight" with no signs of fluid overload), as assessed by their kidney specialist
Who may not be able to join:
- People with poorly controlled diabetes, shown by a blood sugar average (HbA1c) test result above 9%
- People who have had one or more peritonitis infections (infection inside the abdomen) in the last 6 months, or who currently have an infection around their dialysis catheter
- People with low red blood cell levels (anaemia), where haemoglobin is below 8g/dL
- People who are not able to provide written consent or follow the study's instructions
- People who experience urinary incontinence (inability to control bladder)
- People who weigh less than 60kg
- People who have a gut or bowel condition that causes ongoing diarrhoea, or who are expected to lose significant sodium through their stools
- People who have taken the heart medication amiodarone in the last 6 months, as it can interfere with one of the study's tests
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Jeffrey Testani, MD, Yale University
Phone: 2037857917
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Water free Na removal over the 5-day intervention
Can't join this trial?
Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.