Heart Disease Trial, Recruiting NCT06896227 Sponsor: Heinrich-Heine University, Duesseldorf Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT06896227
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have had their aortic heart valve replaced using a catheter-based procedure (called TAVR) where the catheter was inserted through an artery in the groin (transfemoral approach).

Who may not be able to join:

  • People whose TAVR procedure used an access point other than the groin artery (for example, through the chest or arm).
  • People whose procedure involved placing a new valve inside an already-existing replacement valve.
  • People who have previously had a biological (tissue-based) replacement heart valve implanted at any time in the past.
  • People who have a pacemaker, an implantable heart shock device (ICD), or a cardiac resynchronization therapy (CRT) device.
  • People who have been diagnosed with liver cirrhosis (severe scarring of the liver).
  • People who have a condition affecting the esophagus (the tube connecting the throat to the stomach), including swollen veins in the esophagus (esophageal varices).
  • People who have a low platelet count or problems with blood clotting.
  • People who have a medical or psychiatric condition — such as dementia, alcoholism, or substance misuse — that may affect their ability to give informed consent or participate fully in the study, including follow-up visits.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Malte Kelm, Prof., Division of Cardiology, Pulmonary Disease and Vascular Medicine

Phone: 0211 81 18800

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Heinrich-Heine University, Duesseldorf
Registry
ClinicalTrials.gov
Start date
22 October 2024
Est. completion
1 September 2025

Where this trial is recruiting

🇩🇪 Germany

Primary endpoints

Presence of a commissural alignment; Presence of symmetrical position; Transvalvular gradients; Effective orifice area (EOA); Doppler velocity index; Paravalvular leakage; Turbulent flow; Pressure recovery; Energy loss coefficient; global coronary flow reserve; Peak velocity; Wall sheer stress; Flow displacement; aortic area; volumen; LV-Function; RV-Function; Strain

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov