Hearing Loss Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years old or older
• You have been newly diagnosed with a condition called Idiopathic Intracranial Hypertension (IIH) — meaning raised pressure in the skull with no clear cause — within the last 3 months
• A brain scan (MRI) has shown a narrowing in specific veins that drain blood from your brain (called transverse venous sinuses)
• Your MRI results are otherwise normal, apart from findings related to IIH
• You have eye symptoms linked to IIH, including a specific level of swelling of the optic nerve detected during eye examinations (confirm with trial site)
• Your eye scan (OCT) has NOT shown damage to certain cells at the back of your eye (macular ganglion cells)
• You are willing and able to attend all scheduled appointments and follow all trial procedures
• You have signed a consent form after being informed about the trial and data collection
• You are covered by public health insurance

Who may not be able to join:

• You have previously been treated with a medication called acetazolamide for IIH
• You have a known allergy to contrast dye, nickel, or titanium
• You have taken certain medications (such as lithium, vitamin A, or tetracycline) within 2 months of your diagnosis that can raise pressure in the skull
• You have a history of blood clots in the brain's veins or a brain tumour
• You have experienced a rapid and severe loss of vision due to IIH within the past 4 weeks
• Your eye scan (OCT) shows damage to specific cells at the back of your eye (macular ganglion cells)
• You have damage (atrophy) to the optic nerve
• You have a condition called amblyopia (sometimes known as "lazy eye")
• You have a significant prescription for glasses or contacts, alongside certain other eye conditions such as glaucoma (confirm with trial site)
• You are pregnant or a pregnancy test has come back positive
• You have a serious or life-threatening illness that could interfere with the trial or mean you are unlikely to benefit
• There is evidence of bleeding in or around your brain
• Your life expectancy is less than 6 months
• You have chronic (long-term) IIH rather than a new diagnosis
• You have significant kidney problems (confirm specific levels with trial site)
• You have previously had a stent placed in a vein inside your skull
• You have previously had gastric bypass surgery
• You have a medical reason that prevents you from having a general anaesthetic
• You cannot take aspirin, clopidogrel, or similar blood-thinning medications
• You have a history of chronic obstructive pulmonary disease (COPD) or another serious breathing condition
• You have a history of deep vein thrombosis (DVT) or a blood clot in the lungs (pulmonary embolism)
• You have a history of atrial fibrillation (an irregular heartbeat) or other conditions that raise your risk of stroke
• You have certain blood vessel abnormalities in the brain, such as malformations, aneurysms, or significant narrowing of blood vessels (confirm with trial site)
• The shape or structure of your brain's veins would make the procedure unsafe (confirm with trial site)
• You are employed by or dependent on the organisation running the trial
• You have taken part in another clinical trial or received an unapproved medicine within the last 4 weeks
• You are legally protected under the French Public Health Code, including people under legal guardianship, prisoners, or women who are pregnant, recently given birth, or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.