Alzheimer's Disease Trial, Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People between 50 and 80 years of age
- People who have been diagnosed with Alzheimer's disease according to the official diagnostic guidelines set by the National Institute on Aging and the Alzheimer's Association
- People with mild to moderate memory and thinking difficulties, with a specific score of 0.5 to 2 on a standard dementia rating scale called the CDR
- People who have been on a stable medication routine for more than one month and have no plans to change their medications in the 6 months after joining the trial
- People who are willing and able to sign a consent form and follow the trial's requirements
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People whose dementia is caused by something other than Alzheimer's disease, such as strokes, brain infections, Huntington's disease, Parkinson's disease, Lewy body dementia, head injury, poisoning, liver or lung disease affecting the brain, brain tumours, thyroid or other hormone conditions, or vitamin deficiencies
- People who have a serious or unstable health condition affecting the heart, liver, kidneys, digestive system, lungs, nervous system, mental health, immune system, or blood — or any condition the trial doctors believe could affect the study results — or whose life expectancy is less than 24 months
- People who have had cancer in the past 5 years, with some exceptions for certain low-risk or non-spreading cancers (confirm with trial site)
- People who have been diagnosed with a primary mental health condition other than Alzheimer's-related cognitive decline, particularly if the trial doctors believe it could affect how results are interpreted or the person's ability to complete the study; people with a history of schizophrenia or other long-term psychiatric conditions are also excluded
- People who the trial doctors believe may have thoughts of suicide
- People who are unable to read or write, or who have not had enough education to complete the thinking and memory tests used in the trial
- People who have had a history of alcohol or drug misuse (not including smoking) within the 2 years before the screening visit
- People with a history of serious or multiple drug allergies, a strong tendency toward allergic reactions, or severe skin reactions to treatments
- People whose physical check-up, neurological exam, vital signs, heart tracing (ECG), or blood/lab tests during screening show important abnormalities that may be harmful, affect the study, or suggest another cause of dementia (as judged by the trial doctors)
- People whose MRI brain scan shows significant abnormalities that suggest another possible cause of cognitive decline, or findings that could make participation unsafe — for example, more than two large strokes, strokes in critical brain areas, or a high score on a brain white matter scale called the Fazekas Scale
- People who cannot have an MRI scan for any reason, including severe claustrophobia or having certain metal implants or a pacemaker in their body
- People for whom the VNS surgical procedure would be unsafe — for example, due to left vagus nerve damage, severe infection at the surgery site, or heart, lung, liver, or kidney problems that prevent the person from safely undergoing general anaesthesia
- People currently taking part in another interventional clinical trial or medical research study that is considered incompatible with this trial
- People who do not have a reliable, consistent caregiver to support them throughout the trial
- People who are pregnant or planning to become pregnant
- Staff members working at the trial centre, or their immediate family members (spouse, parent, child, or sibling)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Kids Helpline — 24/7, free and private for anyone aged 5 to 25: 1800 55 1800
- headspace — mental health support for 12 to 25 year olds: headspace.org.au
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Principal Investigator: Jianguo Zhang, MD, Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Phone: +86 18101287707
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change From Baseline in ADAS-Cog 14 Score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 3 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.