Phase 4 Heart Disease Trial, Recruiting NCT06934798 Sponsor: University of Sao Paulo Condition: Heart Disease
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Phase 4 Heart Disease Trial, Recruiting

NCT06934798
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 or older.
  • People who have had heart bypass surgery, heart valve surgery, or both, and who develop a condition called vasoplegic syndrome within the first 24 hours after the operation — this means their blood pressure drops too low and does not improve after receiving at least 1 litre of intravenous fluids.

Who may not be able to join:

  • People who are pregnant or breastfeeding.
  • People who have had surgery on the aorta (the main large artery from the heart).
  • People who have had surgery to correct a heart defect present from birth.
  • People who have had a heart transplant.
  • People who underwent emergency surgery.
  • People who were receiving blood pressure-raising medication before their surgery.
  • People who have a mechanical heart-assist device in place after surgery (other than an intra-aortic balloon pump).
  • People who have severely low sodium levels in their blood after surgery (below 130mEq/l).
  • People who experience a heart attack in the period after surgery.
  • People who develop reduced blood flow to the intestines after surgery.
  • People with a history of Raynaud's disease (a condition affecting blood flow to the fingers and toes).
  • People with a history of cancer.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Ludhmila A Hajjar, Full Professor, University of Sao Paulo

Phone: +55 (11) 2661-5795

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
1 April 2024
Est. completion
30 July 2025

Where this trial is recruiting

🇧🇷 Brazil

Primary endpoints

Change in inotropic function assessed by cardiac output between T0 and T1

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov