Alzheimer's Disease Trial, Recruiting NCT06956300 Sponsor: Massachusetts General Hospital Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Recruiting

NCT06956300
Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People between the ages of 40 and 99
  • People who are native English speakers
  • People who are willing and able to give their consent to take part, and to attend brain scans and memory/thinking tests at set times during the study
  • People who are either cognitively normal older adults, or who have preclinical Alzheimer's disease (very early signs of Alzheimer's that have not yet caused noticeable symptoms)

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have had a head injury that caused them to lose consciousness or become confused
  • People who have another major brain or mental health condition
  • People who are known to have a structural problem in their brain, such as a tumour or a stroke-related injury
  • People who cannot have an MRI scan, for example because they have a pacemaker, aneurysm clips, an artificial heart valve, ear implants, or any metal fragments or foreign objects in their eyes, skin, or body
  • People who have had a long history (more than 10 years) of alcohol or drug misuse that continued up until the time their current symptoms began
  • People who have a significant ongoing physical illness or unstable health condition that could make it difficult to follow the study requirements
  • People who are not willing to return for follow-up visits, or to undergo thinking and memory tests, TMS (a non-invasive brain stimulation procedure), or MRI scans
  • People who have a history of seizures that occurred without a clear medical cause
  • People who have a parent or sibling with a seizure disorder
  • People who are currently taking, or plan to take, certain medications considered to carry a higher risk of triggering seizures — including clozapine, high doses of bupropion (over 400mg daily), diphenhydramine, cyclosporine, isoniazid, imipenem, chloroquine, tramadol, or theophylline

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 August 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 6176436348

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
7 April 2025
Est. completion
31 August 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Changes in motivation; Changes in Brain Network Connectivity; Changes in Memory

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov