Phase 2 Rheumatoid Arthritis Trial, Recruiting NCT06972446 Sponsor: AbbVie Condition: Rheumatoid Arthritis
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Phase 2 Rheumatoid Arthritis Trial, Recruiting

NCT06972446
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been treated with at least one biologic or targeted synthetic DMARD (a type of specialist arthritis medication) for 3 months or more at some point before the screening visit, and whose rheumatoid arthritis remained active during that time — or who had to stop taking it due to side effects, regardless of how long they took it. No more than 2 of these specialist medications may have been used previously.
  • People who are currently taking methotrexate at a stable, unchanged dose.

Who may not be able to join:

  • People who are taking anti-inflammatory pain medications (such as NSAIDs), paracetamol, certain milder opioid pain relievers (such as tramadol, codeine, or hydrocodone), oral steroid medications (at low doses equivalent to 10 mg or less of prednisone per day), or inhaled steroids for ongoing conditions — unless the dose has remained unchanged for at least 1 week before the baseline visit.
  • People who have a history of any form of arthritis that began before the age of 17, or who currently have a diagnosed inflammatory joint condition other than rheumatoid arthritis.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: ABBVIE INC., AbbVie

Phone: 844-663-3742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
20 June 2025
Est. completion
1 February 2027

Where this trial is recruiting

🇨🇦 Canada 🇨🇿 Czechia 🇩🇪 Germany 🇭🇺 Hungary 🇵🇱 Poland Puerto Rico 🇷🇸 Serbia 🇸🇰 Slovakia 🇿🇦 South Africa 🇰🇷 South Korea 🇪🇸 Spain 🇹🇼 Taiwan 🇺🇸 United States

Primary endpoints

Percentage of Participants With an American College of Rheumatology 50% (ACR50) Response; Number of Participants with Adverse Events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov