Phase 2 Breast Cancer Trial, Not Yet Recruiting NCT06973525 Sponsor: Hebei Medical University Fourth Hospital Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Not Yet Recruiting

NCT06973525
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have been confirmed by tissue testing to have invasive breast cancer at clinical stage II or III.
  • People aged between 18 and 70 years.
  • People who are generally well enough to carry out daily activities with no or minimal limitations (as measured by a standard health performance scale called ECOG, scoring 0 or 1).
  • People whose breast cancer has been confirmed by tissue testing to be HER2-positive.
  • People whose heart is pumping at or above 55% efficiency (as measured by a heart function test called LVEF).
  • People who have at least one tumour that can be measured using standard imaging guidelines.
  • People whose blood counts and organ function fall within acceptable ranges — including healthy levels of red blood cells, white blood cells, and platelets, as well as normal liver and kidney function (confirm specific values with trial site).
  • People who are not pregnant or breastfeeding; women who could become pregnant must agree to use an approved form of contraception throughout the study treatment and for at least 3 months after the last dose of the study drug.
  • People who are able to understand and are willing to sign a written consent form agreeing to take part.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have stage IV (metastatic) breast cancer, meaning the cancer has spread to other parts of the body.
  • People who have a second, separate cancer diagnosis, except for fully treated skin cancer.
  • People who had a major surgery unrelated to breast cancer within 4 weeks before joining the trial, or who have not fully recovered from such a surgery.
  • People who have had serious heart or blood vessel problems in the 6 months before starting the trial, including severe heart failure, heart attack, stroke, blood clots in the lungs, unstable chest pain, or a heart rhythm problem requiring treatment; or who have a diagnosed heart muscle disease such as dilated or hypertrophic cardiomyopathy; or who have certain heart rhythm abnormalities or an irregular heart rate condition called atrial fibrillation at a significant level; or who have high blood pressure that cannot be adequately managed (confirm with trial site).
  • People who are known to be allergic to any of the components of the drugs used in this trial.
  • People who have a known history of immune system deficiency, including a positive HIV test, other inherited or acquired immune conditions, or a history of organ transplantation.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026

GP referral letter

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Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Hebei Medical University Fourth Hospital
Registry
ClinicalTrials.gov
Start date
1 September 2025
Est. completion
31 May 2027

Primary endpoints

tpCR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov