Sleep Disorders Trial, Recruiting NCT06976138 Sponsor: Johns Hopkins University Condition: Sleep Disorders
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Sleep Disorders Trial, Recruiting

NCT06976138
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with knee osteoarthritis
  • People who are 60 years of age or older
  • People who are scheduled to have a total knee replacement on one knee for osteoarthritis
  • People who have difficulty falling asleep or staying asleep

Who may not be able to join:

  • People who are currently taking any medication to help with sleep
  • People who have already completed a structured talking therapy program specifically for insomnia (called Cognitive Behavioral Therapy for Insomnia)
  • People who have used bright light therapy or negative ion therapy in the past year
  • People who have an inflammatory joint or rheumatic disease, or a seizure disorder
  • People who have a serious mental health condition, Bipolar I disorder, or a problem with substance or alcohol use
  • People who have a serious sleep disorder or body clock (circadian rhythm) disorder, or untreated sleep apnea
  • People who are pregnant or currently breastfeeding
  • People who have a known condition affecting the retina (the back of the eye)
  • People who have had eye surgery (though Lasik or cataract surgery performed more than 3 months ago may be acceptable — confirm with trial site)
  • People who are taking medications that modify how the immune system responds to rheumatic disease
  • People who are taking medications that increase sensitivity to light
  • People who are not willing to stop taking over-the-counter sleep aids, such as melatonin, for at least 2 weeks before enrolling in the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Michael T Smith, PhD, Johns Hopkins University

Phone: 410-550-5704

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
13 June 2025
Est. completion
31 July 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Chronic postsurgical pain as assessed by the Western Ontario and McMaster Universities Osteoarthritis Index

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov