Alzheimer's Disease Trial, Not Yet Recruiting NCT06978946 Sponsor: RenJi Hospital Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Not Yet Recruiting

NCT06978946
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People aged between 50 and 80 years old.
  • People who have been diagnosed with Alzheimer's disease, frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), or Parkinson's disease dementia (PDD), based on specific established diagnostic guidelines for each condition.
  • People whose scores on standard memory and thinking tests fall within a certain range, specifically a Mini-Mental State Examination score below 21, a Montreal Cognitive Assessment score below 17, and a Clinical Dementia Rating score of 2 or higher.
  • People whose doctors have assessed their condition as moderate to severe.
  • People who have been on the same medication routine for at least one month without changes.
  • People who have given signed consent to participate and have shown they are able to follow study requirements.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose dementia is caused by something other than the conditions listed above, such as vascular dementia, brain infections (including HIV or syphilis-related), Creutzfeldt-Jakob disease, Huntington's disease, past brain injury, alcohol or toxic substance exposure, major organ-related conditions affecting the brain (such as liver or lung disease), bleeding under the skull (subdural hematoma), hormone gland disorders (such as thyroid or parathyroid problems), vitamin deficiencies, or any other identified cause.
  • People who have serious or unstable health conditions affecting the heart, liver, kidneys, digestive system, lungs, hormone system, nervous system (other than memory and thinking problems), immune system, or blood, or any other condition that the study doctor believes could affect the results — or people whose life expectancy is less than 24 months.
  • People who currently have a diagnosed psychiatric condition other than memory and thinking problems, or whose psychiatric symptoms the study doctor believes could interfere with cognitive testing or their ability to complete the study — people with a history of schizophrenia or other long-term psychotic disorders are also in this category.
  • People who are not suitable candidates for a specific surgical procedure (deep cervical lymphatic vessel surgery), including those with injury to the left vagus nerve, serious infection at the surgical site, significant heart, lung, liver, or kidney problems, a history of radiation therapy or surgery to the head or neck, a high-risk anaesthetic assessment, or an inability to tolerate lengthy surgery.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 August 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

If this is close to home

This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.

  • Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
  • Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
  • Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
  • Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
  • Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14

Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.

Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

Contact this trial

Phone: +86 18616878901

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
28 May 2025
Est. completion
1 February 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Severity of dementia

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov