Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are aged 45 or older and are of Chinese, Malay, or Indian ethnicity
- People who have been referred to a sleep clinic at one of the participating study centres because sleep apnoea was suspected
- People who have had a full overnight sleep study (done in a clinic) and been diagnosed with moderate-to-severe sleep apnoea, meaning they stopped breathing or had reduced breathing 15 or more times per hour during sleep
- People who have shown early signs of memory or thinking difficulties, based on a specific memory test score (the exact score cut-off depends on how many years of schooling the person had)
- People who agree to follow the study plan throughout the trial
Who may not be able to join:
- People who already knew they had sleep apnoea and are currently receiving regular treatment for it
- People with severe memory or thinking difficulties, based on a very low score on the memory test
- People who had very severe drops in blood oxygen levels during their sleep study (confirm with trial site for exact thresholds)
- People with a known diagnosis of schizophrenia, bipolar disorder, severe depression, drug addiction, or alcohol addiction
- People for whom a mandibular advancement device (a type of dental mouthguard used to treat sleep apnoea) would not be suitable — for example, those with fewer than six teeth on the upper or lower jaw, those who cannot move their jaw forward or open it wide, those with existing jaw joint problems, severe teeth grinding, or serious gum disease
- People with a life expectancy of less than one year
- People who were hospitalised due to a heart attack, stroke, or similar event in the past three months
- People with certain serious heart conditions, including specific types of heart defects present from birth or moderate-to-severe high blood pressure in the lungs
- People who regularly take medications that could affect memory, thinking, or alertness
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Chi-Hang Ronald Lee, MBBS, MD, National University Heart Centre, Singapore
Phone: +6567722493
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Montreal Cognitive Assessment (MoCA)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.