Phase 2 Sjogren's Syndrome Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with Rheumatoid Arthritis (RA):

• You have a confirmed diagnosis of rheumatoid arthritis based on recognised medical criteria.
• Your blood tests show a positive result for Rheumatoid Factor (RF) or a related marker called ACPA.
• Your blood tests show signs of inflammation above a certain level (confirm with trial site).
• You have already tried a biological treatment for at least 12 weeks, and your doctor has determined it did not work well enough.
• You currently have at least 6 swollen joints and 6 tender joints.

For people with Sjögren's Disease:

• You have a confirmed diagnosis of primary Sjögren's Disease based on recognised 2016 criteria, confirmed within the last 24 weeks before joining the trial.
• Your disease activity score (called clinESSDAI) is above 6, meaning your condition is considered moderately to severely active (confirm with trial site).
• You still produce a small amount of saliva when tested.

For people with Inflammatory Muscle Disease (IIM):

• Your blood tests show a positive result for certain immune system markers associated with muscle disease.
• Your condition has not responded well enough, or you could not tolerate, at least 3 months of steroid treatment and/or at least one other medication that suppresses the immune system.
• You have had a muscle biopsy or muscle MRI scan confirming your diagnosis within the last 12 months (where applicable).

For people with Systemic Sclerosis (SSc, also known as scleroderma):

• You have a confirmed diagnosis of systemic sclerosis based on recognised 2013 medical criteria.
• Your skin thickening score (called mRSS) is greater than 10, indicating significant skin involvement (confirm with trial site).
• Your diagnosis was first confirmed within the last 8 years.
• Your condition has not responded well enough, or you could not tolerate, at least 3 months of steroid treatment and/or at least one other immune-suppressing medication.

Who may not be able to join:

• No specific exclusion criteria were listed in the information provided — please confirm any restrictions directly with the trial site.

Important: Always verify eligibility with the trial site directly before applying.