Sjogren's Syndrome
Clinical trials recruiting in Australia for Sjogren's Syndrome, as the public registries list them.
Also called: Sjogren's Disease; Dacryosialoadenopathia atrophicans; Gougerot-Houwer-Sjogren syndrome; Gougerot-Sjogren syndrome; Keratoconjunctivitis sicca; Keratoconjunctivitis sicca-xerostomia; Secreto-inhibitor-xerodermostenosis; Sicca syndrome; Sjogren-Gougerot syndrome
At a glance
8 trials recruiting in Australia
5 states or territories with a listed site
1 started recruiting in the last 30 days
33 trials recruiting overseas
15 October 2026 date last checked
Where the trials are
Listed sites in each state and territory. Choose one to show only the trials with a site there, and choose it again to show them all.
1 listed site on this page does not say which state it is in, so the counts above are lower than the real number of sites in some states. The trials themselves are all listed below.
Trials for Sjogren's Syndrome
8 of 8 trials shown.
This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.
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Recruiting Phase 3
Phase 3 study for people with Sjogren's Syndrome
Where- The Queen Elizabeth Hospital, Woodville South (SA) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor AmgenTimelineStarted 25 February 2025 Today 16 October 2026 Estimated completion 11 December 2029NCT06747949 · Checked 11 October 2026
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Recruiting Not a phased study
Study for people with Sjogren's Syndrome
Where- School of Optometry and Vision Science, Sydney (NSW) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor The University of New South WalesTimelineStarted 1 June 2025 Today 16 October 2026 Estimated completion 30 December 2026NCT06898853 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Sjogren's Syndrome
Where- Sydney Eye Hospital, Sydney (NSW) — Not yet recruiting
- Univ of New South Wales, Sydney (NSW) — Recruiting
- OTA, Brisbane (QLD) — Recruiting
- Queensland University of Technology, Brisbane (QLD) — Recruiting
- University of the Sunshine Coast, Maroochydore (QLD) — Recruiting
- University of Melbourne, Melbourne (VIC) — Recruiting
Who can join Age 18 Years to 80 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Lubris Bio Pty LtdTimelineStarted 17 September 2025 Today 16 October 2026 Estimated completion 30 July 2026Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.
NCT07118241 · Checked 11 October 2026
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Recruiting Phase 1
Phase 1 study for people with Sjogren's Syndrome
Where- Xencor Investigative Site, Melbourne — Recruiting
Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.Sponsor Xencor, Inc.TimelineStarted 24 February 2026 Today 16 October 2026 Estimated completion 1 October 2028NCT07284797 · Checked 11 October 2026
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Recruiting Phase 3
Phase 3 study for people with Sjogren's Syndrome
Where- Novartis Investigative Site, Maroochydore (QLD) — Recruiting
Who can join Age 18 Years and over. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Novartis PharmaceuticalsTimelineStarted 16 July 2026 Today 16 October 2026 Estimated completion 15 August 2029NCT07621809 · Checked 15 October 2026
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Recruiting Phase 1
Phase 1 study for people with Sjogren's Syndrome
Where- Q-Pharm Pty Ltd, Brisbane (QLD) — Recruiting
Who can join Age 18 Years to 75 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.Sponsor Otsuka Pharmaceutical Development & Commercialization, Inc.TimelineStarted 24 September 2026 Today 16 October 2026 Estimated completion 20 November 2028NCT07649265 · Checked 15 October 2026
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Recruiting Phase 1
Phase 1 study for people with Sjogren's Syndrome
Where- Candid Clinical Site, Melbourne (VIC) — Recruiting
Who can join Age 18 Years to 65 Years. Sex Anyone, regardless of sex. Healthy volunteers Accepted.Sponsor Candid TherapeuticsTimelineStarted 20 July 2026 Today 16 October 2026 Estimated completion 31 March 2028NCT07712939 · Checked 11 October 2026
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Recruiting Phase 2
Phase 2 study for people with Sjogren's Syndrome
Where- Novartis Investigative Site, Southport (QLD) — Recruiting
- Novartis Investigative Site, Nedlands (WA) — Recruiting
Who can join Age 18 Years to 100 Years. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.Sponsor Novartis PharmaceuticalsTimelineStarted 24 August 2026 Today 16 October 2026 Estimated completion 19 February 2029NCT07737743 · Checked 15 October 2026
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voxsanity.com.au · trial list from public registries · page built 16 October 2026 · not medical advice
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Trials overseas
33 trials for this condition are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.
These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.
Search ClinicalTrials.gov Search the WHO registry portal Joining a trial overseas
About Sjogren's Syndrome
The text below is reproduced exactly as its source published it. It has not been edited, shortened or rewritten.
What is Sjogren's syndrome? Sjogren's syndrome, also called Sjogren's disease, is a chronic (long-lasting) autoimmune disease. When you have an autoimmune disease, your immune system attacks healthy tissues and organs by mistake. In Sjogren's syndrome, your immune system attacks the glands that make moisture in the eyes, mouth, and other parts of the body. This causes a dry mouth and dry eyes. You may have dryness in other places that need moisture, such as your nose, throat, and skin. Sjogren's can also affect other parts of the body, including your joints, lungs, kidneys, blood vessels, digestive organs, and nerves. What causes Sjogren's syndrome? Normally, your immune system protects the body from infection and disease. But with Sjogren's syndrome and other autoimmune diseases, your immune system attacks healthy tissues and organs. Researchers don't know for sure what causes the immune system to do this. But they think that it is caused by a combination of genetic and environmental factors. Studies have linked Sjogren's syndrome to gene changes in several genes. Some researchers also think that the disease may be triggered by something in the environment. For example, they think that one possible trigger could be a previous infection with a virus or bacteria. Who is more likely to develop Sjogren's syndrome? Most people with Sjogren's syndrome are women. You can get it at any age, but it is most common in people in their 40s and 50s. Sjogren's syndrome is more common in people who have other autoimmune diseases such as rheumatoid arthritis and lupus. This is known as a secondary form of Sjogren's syndrome. People who don't have another autoimmune disease have a primary form of Sjogren's syndrome. What are the symptoms of Sjogren's syndrome? Sjogren's syndrome may have different effects on the body. Not everyone will have the same symptoms. Some people have cycles of mild and then severe symptoms. The two main symptoms are: - Dry eyes. Your eyes may burn or itch or feel like they have sand in them. Sometimes your vision may be blurry, or you could be bothered by bright lights. - Dry mouth. Your tongue and your throat may feel dry. You might have trouble swallowing, speaking, and tasting. Sjogren's syndrome can also affect other parts of the body, causing symptoms such as: - Joint and muscle pain - Dry skin - Rashes on the skin of hands or feet - Numbness or tingling in the hands or feet - Vaginal dryness - Dry cough that doesn't go away - Fatigue that doesn't go away How is Sjogren's syndrome diagnosed? There is no single test for Sjogren's syndrome. To find out if you have it, your provider: - Will ask about your medical history and symptoms. - Will do a physical exam, which includes checking for signs of dry mouth and signs of related autoimmune diseases. - May order tests, including: - Eye tests to see if you produce a normal amount of tears and to find out if your eyes have been damaged by dryness. - Salivary gland tests to measure how much saliva your mouth produces. They could include imaging tests and a biopsy. - Blood tests. What are the treatments for Sjogren's syndrome? There is no cure for Sjogren's syndrome. Treatment focuses on relieving your symptoms. The treatments can be different for each person, depending on which parts of the body are affected. They may include: - Eye drops (artificial tears) or ointments to relieve dryness in the eyes. - Saliva substitutes. - Prescription medicines that cause your salivary glands to make more saliva. - A minor procedure that places small plugs in the tear duct in the corners of the eyes. The plugs block your tears from draining so they stay in your eyes longer. - Medicines to help with other symptoms caused by Sjogren's syndrome, such as medicines for pain and inflammation. - Medicines that suppress (weaken) your immune system (for severe cases). You can also try to relieve some of your symptoms by sucking on sugar-free candy, drinking water often, increasing the humidity in your room, and not smoking. Because having a dry mouth can raise your risk of cavities, it's important to take good care of your teeth and see your dentist regularly.
US source; availability in Australia may differ.
Source: MedlinePlus Health Topics (medlineplus.gov), public domain (U.S. National Library of Medicine). Read the full source.
Sources and dates
- ClinicalTrials.gov – trial records, statuses and site lists
- MedlinePlus – the About text above, reproduced exactly
- ClinicalTrials.gov processing date: 13 October 2026.
- This page last checked by Voxsanity: 15 October 2026.
Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.
Not medical advice.
Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.
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