Fibromyalgia Trial, Recruiting NCT07023523 Sponsor: Brigham and Women's Hospital Condition: Fibromyalgia
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Fibromyalgia Trial, Recruiting

NCT07023523
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People between 18 and 65 years old
  • People who have been diagnosed with fibromyalgia (based on the Wolfe et al. 2011 research criteria) for at least one year
  • People who have been on a stable dose of their current medications and agree not to change their medications, doses, or complementary/alternative treatments during the trial
  • People whose average pain level is at least 4 out of 10, and who experience pain on at least half of all days
  • People who are able to give written consent and are fluent in English

Who may not be able to join:

  • People who have another acute (sudden or short-term) pain condition at the same time
  • People who have another ongoing pain condition that they find more painful than their fibromyalgia
  • People who take stimulant medications for fatigue related to sleep apnea or shift work (for example, modafinil)
  • People who are pregnant or breastfeeding
  • People who have a history of a psychiatric condition involving psychosis, such as schizophrenia or severe personality disorders
  • People who have a history of anxiety disorders, or anxiety symptoms severe enough to interfere with MRI scanning procedures (for example, panic attacks)
  • People who cannot have an MRI scan for medical reasons, such as having metal implants in their body
  • People who have had a significant head injury, for example one that caused a substantial period of unconsciousness
  • People who have been hospitalised for a psychiatric reason in the past 6 months
  • People currently taking part in another treatment-based clinical trial
  • People who are currently experiencing active thoughts of suicide
  • People who have a diagnosed nerve damage condition with a known cause, such as diabetic nerve damage, chemotherapy-related nerve damage, or Guillain-Barré syndrome
  • People who regularly or daily use narcotic medications or substances of abuse
  • People who have an autoimmune or inflammatory disease that causes pain, such as rheumatoid arthritis, lupus, or inflammatory bowel disease
  • People who have had lower limb vascular (blood vessel) surgery or who currently have a blood vessel problem in their lower limbs
  • People whose situation, behaviour, or any other factor leads the study coordinator or principal investigator to believe they would not be able to complete the study, including providing inconsistent or unreliable pain scores (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Jeungchan Lee, PhD, Spaulding Rehabilitation Hospital

Phone: 617-952-6742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
31 October 2025
Est. completion
1 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Changes in brain activity in pain-associated regions such as vPCC/RSC

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov