Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be 18 years of age or older
- You must have been diagnosed with a heart condition called hypertrophic obstructive cardiomyopathy (a thickening of the heart muscle that blocks blood flow)
- You must have been taking the same dose of a medication called mavacamten for at least 12 weeks without any changes
- Your heart's blood flow measurements must be at or below a certain level, both at rest and during a stress test using ultrasound (confirm with trial site)
- Your heart must be pumping at least 50% of its normal capacity at the time you join the study
- Your heart symptoms must be mild — rated as Class I or II on a standard heart symptom scale, meaning you have little to no limitation during everyday activities
Who may not be able to join:
- You have fainted or had a serious fast heart rhythm problem in the 6 months before joining the study
- Your heart's electrical activity shows a reading that is too prolonged on a heart tracing test (confirm with trial site)
- You have a type of irregular heartbeat called atrial fibrillation that comes and goes, shown on a heart tracing test at screening
- You have a constant or long-term irregular heartbeat and have not been taking blood-thinning medication for at least 4 weeks
- You have previously had a procedure or surgery to reduce the thickness of your heart muscle
- During an exercise breathing test, you show signs of dangerous heart rhythm problems or concerning changes in your heart tracing
- You have significant leaking or narrowing of one or more heart valves, seen on an ultrasound of your heart at rest
- You already have an implanted heart device designed to correct dangerous heart rhythms (a defibrillator)
- Your personal risk score for sudden cardiac death is calculated at 4% or higher (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 00498941406774
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence of Treatment-Emergent Adverse Events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.