Phase 1 Liver Cancer Trial, Recruiting NCT07116486 Sponsor: M.D. Anderson Cancer Center Condition: Liver Cancer
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Phase 1 Liver Cancer Trial, Recruiting

NCT07116486
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed through specific imaging results, blood test findings, or a tissue biopsy
  • People whose liver cancer has been identified through detailed scan results that meet certain recognised imaging classification standards (confirm with trial site for specific imaging details)
  • People whose liver cancer has been identified through a blood protein marker (Alpha Fetoprotein) above a certain level, combined with suggestive scan findings
  • People whose liver cancer has been confirmed through a specialised blood vessel imaging procedure or through a tissue sample
  • People whose liver cancer has been assessed as suitable for a specific treatment called Y90 radioembolization (a type of targeted radiation therapy delivered through the blood vessels)
  • People who have already completed standard imaging, staging, and CT scans before the research scans begin
  • People aged 18 or older
  • People of childbearing potential who agree to use an approved form of contraception throughout the study (and for 4 months after the research scan for men)
  • People who are able to understand the study and are willing to sign a written consent form

Who may not be able to join:

  • People under the age of 18
  • People who have liver cancer but whose doctors have determined they are not suitable for Y90 radioembolization as a standalone treatment
  • People who are pregnant or breastfeeding, due to unknown risks from the radioactive tracer used in this study
  • People with poorly controlled diabetes, specifically those with a fasting blood sugar level above 200 mg/dL
  • People with psychiatric conditions or personal circumstances that may make it difficult to follow the study requirements
  • People who have not fully recovered from side effects of previous treatments, or who have had allergic reactions to similar substances used in this type of research

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Simone Krebs, MD, M.D. Anderson Cancer Center

Phone: (713) 563-6726

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
2 December 2025
Est. completion
30 June 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Safety and Adverse Events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov