Phase 2 Breast Cancer Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 to 70 years who are generally well enough to carry out daily activities with little or no limitation (a measure doctors call ECOG performance status 0–1).
- People diagnosed with breast cancer that has grown to a certain size or spread to underarm lymph nodes, based on standard staging categories (clinical T2–T4, or T1c with lymph node involvement).
- People whose breast cancer has been confirmed as HER2-positive through standard laboratory testing (either IHC 3+ or a positive FISH test, following 2018 ASCO/CAP guidelines).
- People with a tumour that can be measured by ultrasound, mammogram, or MRI within one month before joining the trial.
- People whose recent blood and organ function tests (taken within one month before starting chemotherapy) show results within acceptable ranges, including healthy enough levels of white blood cells, red blood cells, platelets, liver enzymes, kidney function, and heart pumping strength (the heart must be pumping at least 50% effectively).
- Women who could become pregnant must have had a negative blood pregnancy test within 14 days before joining the trial.
- People who have read, understood, and signed the trial's informed consent form.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People whose breast cancer has spread to other parts of the body (Stage IV or metastatic disease).
- People who have already received chemotherapy, hormone therapy, targeted therapy, or radiotherapy for their breast cancer, or who have had another cancer within the past three years or currently have another cancer (exceptions may apply for certain cancers treated with surgery alone that have been clear for five or more years, or for previously cured cervical carcinoma in situ or non-melanoma skin cancer — confirm with trial site).
- People who have had a major surgical procedure unrelated to breast cancer within four weeks before enrolling, or who have not fully recovered from such a procedure.
- People with serious heart conditions, including a history of heart failure or poor heart pumping function, uncontrolled irregular heart rhythms, chest pain requiring medication, significant heart valve disease, evidence of a past heart attack on an ECG, or poorly controlled high blood pressure (confirm with trial site for specific thresholds).
- People who, in the treating doctor's judgement, cannot safely receive chemotherapy due to other serious uncontrolled health conditions.
- People with a known allergy or sensitivity to any of the medications used in this trial.
- People with a history of immune system disorders (including HIV), other inherited or acquired immune deficiencies, or who have had an organ transplant.
- People with any other ongoing condition that the trial doctor believes could put them at risk or prevent the trial from being completed properly.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 13603862755
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Pathological Complete Response (pCR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.