Liver Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
This trial has three groups (cohorts). Each group has its own set of criteria.
Group 1 (SOLACE-1):
- Adults aged 18 or older
- Able to complete psychological questionnaires
- Liver function rated as Child-Pugh class A (a measure showing the liver is still working reasonably well)
- Generally well enough to carry out light activity or be fully active (ECOG score of 0 or 1)
- Has provided signed consent to participate
- Expected to live more than 3 months
- Diagnosed with liver cancer (HCC) that cannot be surgically removed, confirmed by tissue sample or imaging scan
- Cancer is at a moderate or advanced stage (BCLC stage B or C)
- Has at least one tumour that can be measured on scans
- About to begin a first course of immunotherapy treatment (a type of cancer treatment that works with the immune system)
Group 2 (SOLACE-2):
- Adults aged 18 or older
- Able to complete psychological questionnaires
- Liver function rated as Child-Pugh class A
- Generally well enough to carry out light activity or be fully active
- Has provided signed consent to participate
- Expected to live more than 3 months, and more than 12 months overall
- Diagnosed with liver cancer (HCC) confirmed by tissue sample after surgery aimed at removing the cancer completely
- Cancer is at stage II or III (based on a specific medical staging system)
- About to start immunotherapy within 4 to 6 weeks after surgery
Group 3 (SOLACE-3):
- Adults aged 18 or older
- Able to complete psychological questionnaires
- Liver function rated as Child-Pugh class A
- Generally well enough to carry out light activity or be fully active
- Has provided signed consent to participate
- Expected to live more than 3 months, and more than 12 months overall
- Diagnosed with liver cancer (HCC) that is considered removable by surgery, confirmed by tissue sample or imaging
- Has at least one tumour that can be measured on scans
- About to begin immunotherapy treatment before surgery
Who may not be able to join:
All three groups share these criteria:
- Currently taking antidepressant or anti-anxiety medications
- Has a previous diagnosis of a psychiatric (mental health) condition
- Has another cancer diagnosis at the same time
- Unable to complete psychological assessments
Group 1 additional criteria:
- Has previously received systemic cancer treatment (medicines that travel through the whole body to treat cancer)
- Has brain metastases (cancer that has spread to the brain) that are causing symptoms
- Liver function score above 7 on the Child-Pugh scale (indicating poorer liver health)
Group 2 additional criteria:
- Has cancer cells remaining after surgery (incomplete removal)
- Liver function rated as Child-Pugh class B or C (indicating poorer liver health)
Group 3 additional criteria:
- Has serious heart, lung, or kidney problems
- Has previously received systemic cancer treatment
- Has brain metastases that are causing symptoms
- Liver function rated as Child-Pugh class B or C
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: + 86 18172681387
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Progression-Free Survival (PFS); Disease-Free Survival (DFS); Pathological Complete Response (pCR) Rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.