Phase 4 Breast Cancer Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 or older.
- People who have been diagnosed with a specific type of breast cancer — hormone receptor-positive (HR+) and HER2-negative — that has either spread to other parts of the body or cannot be surgically removed, confirmed through a tissue or cell sample test.
- People whose cancer continued to grow or spread after being treated with a combination of a CDK4/6 inhibitor and hormone-based therapy, confirmed by imaging scans.
- People who have at least one area of cancer that can be measured or tracked during the trial.
- People who have received no more than 2 rounds of chemotherapy for advanced or metastatic disease.
- People whose heart, liver, kidneys, and overall physical health meet the required levels of function (confirm with trial site for specific details).
- People who have read and signed a consent form agreeing to take part in the trial.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have previously been treated with a type of drug called a topoisomerase 1 (TOP-1) inhibitor.
- People with serious problems affecting the heart, liver, or kidneys, or other significant health conditions.
- People with a history of moderate to severe scarring or inflammation of the lungs (interstitial lung disease) along with reduced lung function.
- People who currently have brain metastases (cancer that has spread to the brain) that are causing symptoms.
- People who have had an allergic reaction to key parts of the type of drug being studied in this trial (confirm specific components with trial site).
- People with active ongoing inflammatory bowel conditions such as ulcerative colitis or Crohn's disease, or a history of a blocked or perforated bowel.
- People with heart or cardiovascular conditions that are not well controlled, such as severe heart failure or a heart attack within the past 6 months.
- People with active infections, including HIV, active hepatitis B, or active hepatitis C.
- People who are currently pregnant or breastfeeding.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Progression-Free Survival (PFS1)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 30 June 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.