Printed from Voxsanity (voxsanity.com.au) — NCT07178210 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Alzheimer's Disease Trial, Recruiting
NCT07178210
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People aged 50 or older.
- People who have been diagnosed with mild to moderate Alzheimer's Disease according to a specific internationally recognised set of diagnostic guidelines (the NIA-AA criteria).
- People who have had a brain scan (amyloid PET) or a spinal fluid test (CSF) that came back positive for markers associated with Alzheimer's Disease.
- People whose score on a standard memory and thinking test (called the MMSE) falls within the mild to moderate range (a score of 10 to 26).
- People whose score on another standard assessment of daily functioning and disease severity (called the CDR-SB) falls within the mild to moderate range (a score of 4.5 to 15.5).
- People who have been found, through pre-procedure imaging, to have certain abnormalities in the lymphatic vessels in the head and neck area.
- People whom the trial doctor considers suitable to undergo a specialised robotic-assisted microsurgery procedure on the lymphatic system, in line with the guidelines for the surgical system being used.
- People who, or whose legally authorised representative, have agreed in writing to take part in the study, attend all required follow-up visits, and complete all study procedures after being fully informed about what the trial involves.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who, or whose legally authorised representative, are unwilling to provide written agreement to participate.
- People where another type of dementia is suspected or confirmed, such as Lewy body dementia, frontotemporal dementia, or vascular dementia.
- People with a known or suspected neurological or brain condition — such as a stroke, brain tumour, seizures, or other brain-related conditions — that could affect their safety in the trial.
- People with a history of radiation treatment to the head or neck area.
- People with severe kidney disease (confirm with trial site regarding the specific kidney function measurement used).
- People who have acute (sudden onset) kidney injury.
- People who currently have an active whole-body infection being treated with antibiotics given through a drip (intravenously).
- People who score above 4 on a standard scale used to measure disability and dependence after a neurological condition (the modified Rankin Score).
- People with significant heart, digestive, breathing, hormonal, or nervous system disorders, or a history of significant mental health conditions, or other conditions that the trial doctor believes could affect the reliability of the study data or the person's ability to follow the study requirements.
- People with a known history of significant bleeding problems, blood clotting disorders, or a condition called Von Willebrand's disease.
- People who currently have an active cancer diagnosis, are currently receiving cancer treatment, or have received cancer treatment within the past 6 months.
- People who are currently receiving, or have received within the past 3 months, a specific type of Alzheimer's treatment known as anti-amyloid-beta monoclonal antibody therapy.
- People who have a medical reason why they cannot have an MRI scan or receive a specific contrast agent (gadobutrol) injected into the spinal fluid.
- People who are currently enrolled in another clinical research study that the trial doctor believes could affect their safety or the results of this trial.
- People whom the trial doctor considers ineligible for any other reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
Contact this trial
Phone: 8336646276
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Recruiting
Phase
Not Applicable
Sponsor
MMI (Medical Microinstruments, Inc.)
Registry
ClinicalTrials.gov
Start date
30 April 2026
Est. completion
30 October 2026
Where this trial is recruiting
🇺🇸 United States
Primary endpoints
Device-related serious adverse events at 30-days
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.