Phase 1 Sleep Disorders Trial, Recruiting (NCT07224074)

Phase 1 Sleep Disorders Trial, Recruiting NCT07224074 Sponsor: Johns Hopkins University Condition: Sleep Disorders

Printed from Voxsanity (voxsanity.com.au) — NCT07224074 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Sleep Disorders

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Adults between 18 and 50 years old
People with a body mass index (a measure of body weight relative to height) between 18 and 30

Who may not be able to join:

People who have a sleep disorder such as sleep apnea, insomnia, restless leg syndrome, narcolepsy, or a condition causing excessive daytime sleepiness
People who have not been diagnosed with sleep apnea but score 5 or higher on a specific sleep apnea risk questionnaire called the STOP-BANG (confirm with trial site)
People who have an uncontrolled breathing or lung condition during the day, such as uncontrolled asthma, uncontrolled COPD, pneumonia, or scarring/inflammation of the lungs
People with a known history of chronic kidney disease or diabetes (either type 1 or type 2)
People who use supplemental (extra) oxygen
People following a very low carbohydrate diet (less than 130g of carbohydrates per day), a ketogenic diet, intermittent fasting, or taking ketone supplements
People who are pregnant or breastfeeding
People taking certain medications, including acetazolamide, a type of diabetes drug called an SGLT2 inhibitor, or daily opioid (strong painkiller) medications
People who have a history of claustrophobia (fear of enclosed spaces) or panic disorder (confirm with trial site)
People who drink alcohol frequently, defined as more than 1 drink per day on average or more than 10 drinks per week

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 2 July 2026

Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07224074

Sponsor: Johns Hopkins University

Phase: Phase 1

Status: Recruiting

Condition: Sleep Disorders

More information: https://clinicaltrials.gov/study/NCT07224074

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Adults between 18 and 50 years old
People with a body mass index (a measure of body weight relative to height) between 18 and 30

Who may not be able to join:

People who have a sleep disorder such as sleep apnea, insomnia, restless leg syndrome, narcolepsy, or a condition causing excessive daytime sleepiness
People who have not been diagnosed with sleep apnea but score 5 or higher on a specific sleep apnea risk questionnaire called the STOP-BANG (confirm with trial site)
People who have an uncontrolled breathing or lung condition during the day, such as uncontrolled asthma, uncontrolled COPD, pneumonia, or scarring/inflammation of the lungs
People with a known history of chronic kidney disease or diabetes (either type 1 or type 2)
People who use supplemental (extra) oxygen
People following a very low carbohydrate diet (less than 130g of carbohydrates per day), a ketogenic diet, intermittent fasting, or taking ketone supplements
People who are pregnant or breastfeeding
People taking certain medications, including acetazolamide, a type of diabetes drug called an SGLT2 inhibitor, or daily opioid (strong painkiller) medications
People who have a history of claustrophobia (fear of enclosed spaces) or panic disorder (confirm with trial site)
People who drink alcohol frequently, defined as more than 1 drink per day on average or more than 10 drinks per week

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 2 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 1

Sponsor

Johns Hopkins University

Registry

ClinicalTrials.gov

Start date

18 December 2025

Est. completion

1 January 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Beta hydroxybutyrate (BHB) maximal concentration (Cmax)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov