Phase 3 Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with systemic sclerosis (SSc) and are between 18 and 70 years old
- People whose SSc was diagnosed using the internationally recognised 2013 ACR/EULAR classification criteria
- People who have long-lasting, persistent itching (chronic pruritus)
- People who are either not taking steroids, or are taking a low dose (no more than the equivalent of 10 mg per day of prednisolone)
- People who have been on a stable, unchanged dose of steroids, immune-suppressing medications, and/or vitamins or supplements for at least 2 weeks before joining the trial
- People who have stopped using moisturiser treatments at least 1 week before the trial's randomisation stage
- People who have stopped taking anti-anxiety medications, sleeping tablets, or hypnotic medications at least 2 weeks before joining the trial
- People who can read and write in the Thai language
Who may not be able to join:
- People whose SSc overlaps with another connective tissue disease
- People who are pregnant or currently breastfeeding
- People who are bedridden and unable to perform any self-care
- People who have an active cancer or malignant disease
- People who have poorly controlled or severe health conditions, including diabetes, asthma, angina, heart or cardiovascular disease, thyroid disease, liver or bile duct disease (including cholestasis), or kidney disease with elevated creatinine levels (confirm with trial site)
- People who have an active infection currently requiring antibiotic treatment taken throughout the body (systemic antibiotics)
- People who have had a previous allergic reaction to urea cream, cannabinoids, or related substances
- People who are currently using illegal drugs such as amphetamines or cocaine
- People who are currently taking anti-anxiety medications, sleeping tablets, or hypnotic medications
- People whose immune-suppressing medication dose currently needs to be adjusted
- People with a history of schizophrenia, or a currently active mood disorder or anxiety disorder
- People who have a skin condition that itself causes itching, such as eczema, psoriasis, scabies, or other listed skin diseases (confirm with trial site for the full list)
- People who have another medical condition — separate from SSc — that is known to cause itching, such as certain neurological diseases or polycythemia vera
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 6643363746
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
The changing of intensity of pruritus evaluated by visual analogue scale (VAS) compared to baseline and a comparison between treatment and control group
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.