Phase 2 Depression and Anxiety Trial, Recruiting NCT07251491 Sponsor: James J. Peters Veterans Affairs Medical Center Condition: Depression and Anxiety
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Phase 2 Depression and Anxiety Trial, Recruiting

NCT07251491
Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who are able and willing to give their formal agreement to take part in the study
  • People who have had a spinal cord injury for at least 1 year
  • People who have a confirmed diagnosis of depression
  • People who are at least 22 years old at the time of joining
  • People who weigh at least 50 kg (110 lbs.)
  • People who breathe completely on their own, without any machine or device to assist breathing
  • People who speak and read English fluently
  • People who are able to swallow pills
  • People who agree to have their study visits recorded with both audio and video
  • People who agree to allow the study team to access their outside medical and psychiatric records
  • People who are able and willing to gradually reduce their antidepressant medication under the supervision of a doctor
  • People who agree to use appropriate contraception during the study

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who are unable to give proper informed consent to participate
  • People who have used psilocybin or any other psychedelic substance in the past 6 months
  • People who have received Electroconvulsive Therapy (ECT) — a treatment that uses electrical currents — within the past 12 weeks
  • People who have used ketamine within the past 12 weeks
  • People who have a history of Bipolar I Disorder
  • People who currently have an eating disorder
  • People who have had a severe alcohol or cannabis use disorder within the past 6 months
  • People who have had a problem with misuse of illicit or prescription drugs within the past 12 months
  • People who are currently considered to be at serious risk of suicide
  • People who have a history of heart attack, aneurysm, or stroke
  • People who have high blood pressure that is not well controlled
  • People who are currently pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 July 2026

If you need support right now

This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.

If you or someone else is in immediate danger, call 000.

  • Lifeline — 24/7 crisis support: 13 11 14
  • Suicide Call Back Service — 24/7 counselling: 1300 659 467
  • 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
  • Beyond Blue — 24/7 mental health support: 1300 22 4636
  • Emergency: 000

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.

Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

Contact this trial

Principal Investigator: Jill M Wecht, EdD, James J Peters VA Medical Center

Phone: 718-584-9000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
James J. Peters Veterans Affairs Medical Center
Registry
ClinicalTrials.gov
Start date
1 May 2026
Est. completion
1 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Number of Participants with Treatment-Related Adverse Events as Assessed by the Adverse Events Log.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov