Hearing Loss Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You must be at least 3 years old
- You must have been diagnosed with Usher syndrome type 1 (a condition causing profound deafness from birth, balance problems, and progressive vision loss) in both eyes, confirmed by a specific genetic test showing changes in both copies of the MYO7A gene
- You must be covered by the French social security system
If you are also taking part in the virtual reality mobility and visual search tests, these extra conditions apply:
- You must have enough knowledge of spoken or signed French to understand the tasks and instructions
- You must have a cochlear implant that allows you to hear and understand spoken instructions during the virtual reality test, and score at least 20 out of 25 on a basic memory and thinking assessment
- You must be between 18 and 75 years old
Who may not be able to join:
- You are not able to attend all of the required study visits
- You are planning to join another experimental treatment trial at any point during this study
- You have other eye conditions affecting your eyes beyond the vision loss related to your diagnosis (for example, a history of retinal detachment, glaucoma, or diabetic eye disease)
- You previously took part in a specific gene therapy trial called USHSTAT (NCT01505062)
- You are currently pregnant, recently gave birth, or are breastfeeding
- You are currently subject to a court or government order restricting your freedom
- You are an adult under a legal guardianship arrangement or are unable to give your own consent to participate
If you are also taking part in the virtual reality mobility and visual search tests, these extra reasons may apply:
- Your score on the memory and thinking assessment (without vision-related questions) is 20 out of 25 or below (confirm with trial site)
- You have a physical or mental difficulty that could interfere with moving around during the test
- You are taking medication that could affect your movement, vision, or thinking during the study assessments (confirm with trial site)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Isabelle Audo, Pr, Centre National d'Ophtalmologie des Quinze-Vingts
Phone: +330140021430
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Best Corrected Visual Acuity (BCVA); Electroretinography (ERG); Full-field stimulus testing (FST)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.