Phase 3 Liver Cancer Trial, Recruiting NCT07302919 Sponsor: University Hospital, Basel, Switzerland Condition: Liver Cancer
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Phase 3 Liver Cancer Trial, Recruiting

NCT07302919
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have signed a consent form agreeing to take part in the study
  • People aged 18 or older
  • People who have been diagnosed with hepatocellular carcinoma (a type of liver cancer), confirmed either by a tissue biopsy or by CT or MRI scan using standard diagnostic criteria
  • People who have at least one tumor that has not previously been treated
  • People whose untreated tumor measures between 3 cm and 8 cm in size
  • People whose liver is functioning reasonably well — meaning no yellowing of the skin (jaundice), no fluid buildup in the abdomen (ascites), and no signs of confusion caused by liver failure
  • Women who could become pregnant must agree to either avoid heterosexual intercourse or use contraception for at least 3 months after treatment

Who may not be able to join:

  • People who have previously received systemic (whole-body) drug treatment for advanced liver cancer
  • People whose cancer has spread widely through the liver, spread to other parts of the body, or grown into blood vessels
  • People who have liver-related confusion or brain problems caused by liver failure (hepatic encephalopathy)
  • People with uncontrolled fluid buildup in the abdomen or around the lungs
  • People who have yellowing of the skin or eyes (jaundice)
  • People with severely low blood pressure, circulatory collapse, or who need medications to maintain blood pressure
  • People with severe heart failure (classified as the most serious level, known as NYHA Class IV)
  • People with significantly reduced kidney function, as measured by a specific blood test formula (confirm with trial site)
  • People who have had a heart attack within the past 6 months
  • People whose life expectancy is less than 12 weeks
  • People who have a known allergy or sensitivity to a class of medications called calcium antagonists, or other reasons they cannot safely receive the drugs being studied
  • People who, for reasons such as language barriers, psychological conditions, or dementia, would be unable to follow the study procedures
  • People who are pregnant, breastfeeding, or planning to become pregnant during treatment or within at least 3 months after treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Fahim Ebrahimi, PD Dr., University Hospital, Basel, Switzerland

Phone: +41 61 777 74 00

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
University Hospital, Basel, Switzerland
Registry
ClinicalTrials.gov
Start date
16 February 2026
Est. completion
1 June 2028

Where this trial is recruiting

🇨🇭 Switzerland

Primary endpoints

complete response rate (CRR); progression-free survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov