Phase 3 Sleep Disorders Trial, Recruiting NCT07332442 Sponsor: Yale University Condition: Sleep Disorders
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Phase 3 Sleep Disorders Trial, Recruiting

NCT07332442
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are able to give your consent to take part in the study.
  • You have recently been diagnosed with obstructive sleep apnea (OSA), confirmed by a sleep test showing you stop breathing or have disrupted breathing at least 10 times per hour during sleep.

Who may not be able to join:

  • You have a sleep or breathing problem that is caused by something other than obstructive sleep apnea, such as a neurological, nerve, muscle, or lung condition.
  • You currently take medications to help you sleep, such as sleeping pills, benzodiazepines, certain antihistamines, trazodone, opioids, or barbiturates.
  • You have had an allergic reaction to a medication called eszopiclone in the past.
  • You have a medical reason why eszopiclone would not be safe for you, such as dizziness, balance problems, or difficulty moving around (confirm with trial site).
  • You have a history of unusual or complex behaviors during sleep, such as sleepwalking or acting out dreams.
  • You regularly drink 2 or more alcoholic drinks per night, or use other substances that slow down the brain and nervous system, in the 2 weeks before or during the study.
  • You are not able to get at least 7 hours of sleep opportunity per night.
  • You have severe active depression or another serious mental health condition, such as schizophrenia, bipolar disorder, or a personality disorder.
  • You have a history of sleepwalking, sleep-driving, or doing other activities while not fully awake.
  • You have previously had a car accident or a near-miss while driving due to feeling sleepy.
  • You have serious liver problems, shown by liver test results that are more than twice the normal level.
  • You have an unstable or very serious medical condition, such as severe heart failure, advanced lung disease, or end-stage kidney disease.
  • You are a woman who is pregnant, breastfeeding, planning to become pregnant, or currently going through egg donation.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Audrey Zinchuk,, MD, MHS, Yale University

Phone: 475-655-6199

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
18 May 2026
Est. completion
1 January 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

CPAP adherence; Flanker inhibitory control and attention test

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov