Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 30 or older who have been diagnosed with stable coronary artery disease (a long-term heart condition affecting the arteries) and a specific type of dental root infection called chronic apical periodontitis.
- People whose heart condition meets the definition used by the Brazilian Society of Cardiology, meaning they have a documented history of at least one of the following, occurring at least 6 months before joining the study: a heart attack; stable chest pain or signs of reduced blood flow to the heart on tests; heart bypass surgery or a procedure to open blocked arteries; or a blocked artery of more than 50% as shown by a special heart imaging test (confirm with trial site).
- People who have at least one tooth with a confirmed infection at the root tip, shown by a dark spot of 3mm or larger on a dental X-ray, a score of 3 or higher on a standard dental rating scale, and a non-vital (dead) tooth nerve confirmed by cold and electrical sensitivity tests.
Who may not be able to join:
- People who have other long-term health conditions that are known to affect inflammation or are linked to gum disease, such as diabetes, rheumatoid arthritis, rheumatic fever, cancer, breathing conditions, or kidney disease.
- People who have gum disease (periodontal disease), whether affecting one area or more widespread across the mouth.
- People who are currently experiencing acute (sudden or severe) symptoms.
- People who have a history of smoking.
- People who have recently had conditions known to affect the body's inflammation levels, such as a bone injury, surgery, or a viral infection.
- People who have taken certain medications in the past 3 months that are known to affect inflammation, including steroids, immune-suppressing drugs, hormone replacement therapy, contraceptives, or antibiotics.
- People with a body mass index (BMI) of 30 or higher (a measure of body weight relative to height).
- People who are pregnant or breastfeeding.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +919991772647
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
To evaluate the levels of hs-CRP and IL-6 in CAD patients with apical periodontitis.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.