Phase 1 HIV and AIDS Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older at the time of screening
- People who are willing and able to give written consent to take part in the study
- People who are in good general health, based on medical history, physical check-up, vital signs, and lab test results at screening
- People whose recent HIV test (within four weeks of enrolling) came back negative
- People whose kidneys are functioning well enough, based on a specific blood test measuring kidney filtration rate (confirm with trial site for exact threshold)
- People who agree to use condoms for all sexual activity during the study
- People who are willing to avoid taking any HIV prevention medication (PrEP) outside of what is provided by the study, for the full duration of the trial
Who may not be able to join:
- People who have used oral PrEP medications (F/TDF or F/TAF) in the two months before joining the study
- People whose HIV test at screening comes back positive or reactive
- People who test positive for hepatitis B surface antigen, which indicates a hepatitis B infection
- People who have had surgery that removed or altered part of their stomach or bowel, such as a gastrectomy, colostomy, or ileostomy, or any procedure that may affect how the body absorbs medication
- People with a recent history of behaviours considered high-risk for HIV, such as sharing needles or having unprotected sex with one or more partners in the two weeks before screening
- People currently taking certain medications that are known to interfere with how the body absorbs the study drug (confirm specific medications with trial site)
- People who are pregnant or breastfeeding
- People with serious, uncontrolled, or progressive health conditions — including issues related to substance use, kidney, liver, blood, digestive, hormonal, lung, nerve, or brain health — that a doctor determines would make participation unsafe or unsuitable
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Sunil Solomon, MD, Johns Hopkins University
Phone: 410-955-1318
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Intracellular tenofovir-diphosphate concentrations (fmol/10^6)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.