Alzheimer's Disease Trial, Not Yet Recruiting NCT07353359 Sponsor: Xuanwu Hospital, Beijing Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Not Yet Recruiting

NCT07353359
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People aged between 50 and 75 years, of any gender.
  • People who have been diagnosed with moderate-to-severe obstructive sleep apnea (a condition where breathing repeatedly stops during sleep) through an overnight sleep study, with a breathing disruption score of 15 or more events per hour.
  • People whose memory and thinking assessment results fall within a range consistent with mild cognitive impairment — a stage of noticeable but not severe changes in memory or thinking (confirm with trial site for specific test score requirements).
  • People who have successfully completed a short trial of wearing the iNAP device (a treatment device worn in the mouth) for 30 minutes without significant discomfort, nausea, or other reactions.
  • People who are taking medications for memory or thinking (such as certain prescription drugs for cognitive symptoms), provided the dose has remained unchanged for at least 12 weeks before the start of the trial.
  • People who are willing to give their signed consent to participate and to attend follow-up appointments as required.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People with a known allergy to silicone, or who have severe nasal blockage conditions (such as nasal polyps or significant chronic nasal inflammation) that make breathing through the nose difficult.
  • People who have had a serious heart or brain event (such as a heart attack or stroke) or a severe flare-up of a significant lung condition in the past 6 months.
  • People who have another sleep disorder (such as chronic insomnia, narcolepsy, or restless legs syndrome) that could affect how sleep apnea is measured.
  • People who have a diagnosed central nervous system condition (such as epilepsy or after-effects of a brain infection) or a severe mental health condition (such as schizophrenia or serious depression).
  • People who have severe difficulties with speech or a physical disability that would prevent them from completing thinking and memory assessments.
  • People who have any condition that affects their level of consciousness or awareness.
  • People who currently have a diagnosis of depression or another psychiatric disorder.
  • People with a history of alcohol dependence, drug addiction, or a neurological condition known to affect memory and thinking (such as a significant past head injury, epilepsy, brain infection, or a condition called normal pressure hydrocephalus).
  • People who are currently taking part in another clinical trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 00861083199456

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Xuanwu Hospital, Beijing
Registry
ClinicalTrials.gov
Start date
15 January 2026
Est. completion
31 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in MoCA Score from Baseline to Week 24

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov