Sleep Disorders Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have signed a consent form agreeing to take part
- People who have been diagnosed with isolated REM Sleep Behavior Disorder (a sleep condition where a person acts out dreams), confirmed by an overnight sleep study, AND who also either: have early signs of movement difficulties plus an abnormal sense of smell, OR have been diagnosed with Parkinson's disease for less than 2 years
- People who are not currently taking, and are not expected to start taking, medications that affect dopamine levels during the study
- People who are able to use the study device on their own or with the help of someone they live with, and who have a stable living situation
- People with sufficient skills in German, French, or Italian
- Women who could become pregnant must have a negative pregnancy test at the time of joining
Who may not be able to join:
- People who have a history of not following other prescribed treatments
- People who are currently or have recently been part of another clinical trial
- People who expect to be away for extended periods during the study
- People with hearing difficulties that would prevent them from hearing the tones used in the study
- People whose sleep study during the screening phase shows they do not respond to the sound-based stimulation used in this trial
- People with a significant or unstable medical condition
- People with a sleep-breathing disorder score above a certain level, or who use a CPAP breathing machine at night
- People who have Restless Legs Syndrome
- People who meet the criteria for an atypical form of Parkinson's disease
- People who have been diagnosed with dementia, or who score below a certain level on a standard memory and thinking test
- People with severe depression or another significant psychiatric condition
- People who regularly use sleeping tablets (benzodiazepines) or other substances that slow down the central nervous system
- People with a current or recent history (within the past year) of substance misuse or heavy alcohol use
- People who have recently had, or are planning to have, major surgery
- People with known allergies or sensitivities relevant to skin electrodes or medications used in the study
- People who do not meet the additional requirements related to the PET brain imaging part of the study (confirm with trial site)
- People for whom participation would pose any other kind of personal risk
- Women who are breastfeeding, planning to become pregnant, or who are unwilling to use a reliable form of contraception during the study
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Andreas Luft, Prof. Dr. med., University of Zurich
Phone: +41 44 255 10 43
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Presynaptic Dopaminergic Integrity
Can't join this trial?
Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.