Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged between 18 and 70 years old
• People who have been diagnosed with obstructive sleep apnea (a condition where breathing repeatedly stops during sleep) through an overnight sleep study, either with a moderate level of breathing disruptions plus symptoms such as daytime sleepiness, waking up gasping, or a partner who has noticed snoring or breathing pauses, or with a higher level of breathing disruptions even without symptoms
• People whose blood pressure falls into one of these categories: slightly elevated blood pressure (120–139/80–89 mmHg) with no more than 2 heart or blood vessel risk factors; newly diagnosed higher blood pressure (140–159/90–99 mmHg) with no heart or blood vessel risk factors; currently on stable blood pressure medication but blood pressure has not yet reached normal levels at a low-risk level; or any person without high cardiovascular risk who is willing to try three months of CPAP treatment and attend follow-up appointments (confirm with trial site)
• People who are able to wear a blood pressure monitor for 24 hours and a continuous blood pressure monitoring device

Who may not be able to join:

• People who have already been diagnosed with sleep apnea and are currently receiving treatment for it, such as CPAP, a dental device, or surgery
• People whose high blood pressure is caused by another medical condition unrelated to sleep apnea, such as kidney artery narrowing, kidney disease, Cushing's syndrome, or a hormone-producing condition called primary aldosteronism
• People who have had a heart attack, stroke, or major surgery in the past 3 months, or who have severe daytime sleepiness, significant memory or thinking problems, active mental illness, or problems with drug or alcohol use
• People with rheumatic or immune system diseases, or with cancer
• People with diseases affecting the large blood vessels, such as giant cell arteritis, a tear in an artery wall, or an aneurysm
• People with conditions that make blood pressure readings unreliable, such as an irregular heartbeat (atrial fibrillation) or blood vessel disease in the arms
• People with a specific inherited form of high blood pressure that begins at a young age (early-onset familial hypertension)
• People who have used any prescription or over-the-counter sleep aid in the four weeks before joining, including medications such as benzodiazepines, zopiclone-type drugs, melatonin-based medications, trazodone, or sedating antidepressants or antihistamines
• People who are allergic to or medically unable to take trazodone or zopiclone, which are potential study medications
• People who are pregnant, breastfeeding, or planning to become pregnant
• People who regularly work night shifts three or more nights per week, or who have been diagnosed by a doctor with a circadian rhythm (body clock) disorder
• People who are already taking part in another clinical trial that involves a treatment or intervention

Important: Always verify eligibility with the trial site directly before applying.