Breast Cancer Trial, Not Yet Recruiting NCT07372339 Sponsor: The First Affiliated Hospital with Nanjing Medical University Condition: Breast Cancer
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Breast Cancer Trial, Not Yet Recruiting

NCT07372339
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Women between the ages of 18 and 70.
  • People who have been diagnosed with breast cancer on one side only, confirmed by a biopsy or tissue test before surgery.
  • People who are planned to have a nipple-sparing mastectomy (removal of the breast while keeping the nipple) with an implant placed in front of the chest muscle at the same time.
  • People whose breast cancer is either an invasive type with a tumour no larger than 5 cm, or a non-invasive type called ductal carcinoma in situ (DCIS).
  • People whose pre-surgery scans show the tumour is at least 1 cm away from the nipple and surrounding dark skin area.
  • People where there is no sign that the cancer has spread to the nipple area, the skin, or the chest muscle — the cancer must be contained within the breast tissue.
  • People where there is no sign the cancer has spread to other parts of the body.
  • People whose lymph nodes do not show signs of cancer based on pre-surgery examination.
  • People who have not had chemotherapy or radiotherapy before surgery.
  • People who are generally well and able to carry out everyday activities with little to no limitation (confirm with trial site for exact fitness level required).
  • People who are willing and able to understand the study, sign a consent form, follow the study procedures, and attend follow-up appointments.
  • People whose surgery will be performed by a surgeon who has carried out at least 30 nipple-sparing mastectomies with implant reconstruction.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People diagnosed with Paget's disease of the breast, a return of breast cancer after previous treatment, or who have had radiation therapy to the chest area in the past.
  • People where the cancer has spread to the skin (including inflammatory breast cancer), the nipple area, or the chest muscle.
  • People who are pregnant or breastfeeding at the time of joining the trial.
  • People who need further surgery to remove more tissue after a previous breast biopsy, or who have had any prior breast surgery (such as breast enlargement, breast reduction, or partial breast removal).
  • People with a breast size larger than a D-cup.
  • People with a body mass index (BMI) over 30 (a measure of body weight relative to height).
  • People with severe breast drooping where the nipple sits below the natural breast crease.
  • People with existing nipple or areola abnormalities (such as inverted nipple or underdeveloped areola), active skin conditions on the breast (such as eczema, skin infection, or ulceration), or significant scarring in the area where surgery would take place.
  • People with serious ongoing health conditions such as a weakened immune system, poorly controlled diabetes, severe heart or lung problems, blood clotting disorders, or any condition that makes general anaesthesia unsafe.
  • People with a known allergy or sensitivity to silicone implants, or to anaesthetic or antibiotic medicines used around the time of surgery.
  • People with pre-existing nerve or neurological conditions (such as nerve damage from diabetes, Parkinson's disease, or spinal cord injury), or who regularly take medicines known to affect nerve or sensory function (such as certain antidepressants or epilepsy medications).
  • People who currently smoke more than 20 cigarettes per day.
  • People who currently misuse alcohol or are dependent on other substances.
  • People who have, or have had, another active cancer diagnosis.
  • People who are unlikely to be able to attend follow-up appointments or complete the required post-surgery check-ups.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 13814162016

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
1 March 2026
Est. completion
1 March 2028

Primary endpoints

Average breast sensory thresholds at 6 months post breast reconstruction as measured by Semmes-Weinstein Monofilaments

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov