Phase 2 Breast Cancer Trial, Not Yet Recruiting NCT07416253 Sponsor: Henan Cancer Hospital Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Not Yet Recruiting

NCT07416253
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Women aged 18 to 75 who have not previously received any treatment for their breast cancer.
  • People with a good general level of physical functioning, able to carry out normal daily activities with little or no limitation (confirm with trial site for specific scoring criteria).
  • People who have been diagnosed with a specific type of breast cancer called HER2-positive, confirmed through laboratory testing of tumour tissue, at an early or locally advanced stage, and whose hormone receptor status (ER/PR) is known.
  • People whose body organs such as the heart, liver, kidneys, and blood system are functioning adequately based on recent test results.
  • Women who are not pregnant at the time of joining, and who agree to use effective contraception during the trial.
  • People who are willing to read and sign a consent form agreeing to take part.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People with bilateral breast cancer (cancer in both breasts), inflammatory breast cancer, or a type where the tumour cannot be found (occult breast cancer).
  • People who have previously received any cancer treatment such as chemotherapy, radiation therapy, or targeted therapy, or who have had radiation treatment within a recent period before the trial starts.
  • People who are receiving other cancer treatments at the same time, or who have had another cancer diagnosis within the past 5 years (with some exceptions for certain fully treated skin or cervical conditions).
  • People who have taken part in another clinical trial within the past 4 weeks, or who have taken strong immune-suppressing or steroid medications above a certain dose within 2 weeks before joining (everyday nasal or inhaled steroids are generally excluded from this rule — confirm with trial site).
  • People who have received a live or weakened (attenuated) vaccine in the past 4 weeks, or who have had a major non-breast surgery within 4 weeks before starting and have not fully recovered.
  • People with an active or recurring autoimmune disease (some well-controlled conditions such as an underactive thyroid, certain skin conditions, or type 1 diabetes may be considered — confirm with trial site), or people with a weakened immune system such as those who are HIV-positive or have had an organ transplant.
  • People with serious uncontrolled heart or blood vessel conditions, such as a heart attack or stroke in the past 6 months, severe heart failure, or an abnormal heart rhythm reading above a certain level on an ECG.
  • People with active serious lung disease, active hepatitis B or C infection at certain levels, or a serious infection currently requiring treatment.
  • People with a tendency to bleed or form blood clots, or who have a known allergy or sensitivity to the study drugs or their ingredients.
  • Women who are pregnant or breastfeeding, or women of childbearing potential who have a positive pregnancy test or who are unwilling to use contraception.
  • People with other significant health conditions — such as uncontrolled high blood pressure, uncontrolled diabetes, or certain neurological or psychiatric conditions — that the trial doctor considers would make participation unsuitable.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 30 July 2026

Contact this trial

Phone: 13603862755

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Henan Cancer Hospital
Registry
ClinicalTrials.gov
Start date
1 March 2026
Est. completion
1 March 2027

Primary endpoints

Pathological Complete Response Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 30 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov