Liver Cancer Trial, Recruiting NCT07429864 Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS Condition: Liver Cancer
Back to Liver Cancer

Liver Cancer Trial, Recruiting

NCT07429864
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have chronic hepatitis or mild, stable liver cirrhosis caused by the hepatitis D virus (HDV)
  • People who have tested positive for HDV in their blood within the 24 weeks before joining the trial
  • People who are already taking antiviral medication for hepatitis B (HBV) at the time of joining
  • People who have been prescribed the medication Bulevirtide 2 mg for the first time within 30 days before joining
  • People of Caucasian ethnicity
  • People aged 18 years or older
  • People who eat a normal, balanced diet that includes both plant and animal foods
  • People who have not taken antibiotics, probiotics, or prebiotics in the month before joining
  • People who have read and signed a consent form agreeing to take part in the trial

Who may not be able to join:

  • People whose liver cirrhosis is at an advanced or decompensated stage (meaning the liver is no longer able to function adequately)
  • People whose liver condition is not caused by a hepatitis B and D co-infection
  • People aged 18 years or younger
  • People who are pregnant or breastfeeding
  • People who have a serious illness that significantly shortens life expectancy, such as certain cancers, severe heart failure, or severe chronic lung disease
  • People with conditions such as coeliac disease or chronic inflammatory bowel disease, or who are taking medications such as antibiotics, probiotics, or prebiotics, that could affect the balance of bacteria in the gut

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Francesca Romana Ponziani, Fondazione Policlinico A. Gemelli IRCCS

Phone: +390630159336

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 September 2025
Est. completion
1 October 2027

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Gut Microbiota in HBV-HDV Patients on Bulevirtide; Bile Acids in HBV-HDV Patients on Bulevirtide; Inflammation in HBV-HDV Patients on Bulevirtide

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov