Phase 1 Heart Disease Trial, Recruiting (NCT07444398)

Phase 1 Heart Disease Trial, Recruiting NCT07444398 Sponsor: Khawaja Danish Ali Condition: Heart Disease

Printed from Voxsanity (voxsanity.com.au) — NCT07444398 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Heart Disease

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You have been diagnosed with a serious form of heart failure where your heart is not pumping well (specifically, where the heart pumps out 45% or less of its blood with each beat), AND you are experiencing severe breathlessness or fatigue that limits daily activities, or worsening moderate symptoms
Your blood test shows elevated levels of a heart stress marker called NT-proBNP — above 1000 pg/mL if your heart rhythm is normal, or above 1600 pg/mL if you have an irregular heartbeat condition called atrial fibrillation

Who may not be able to join:

Your blood pressure is below 100 mmHg (considered low blood pressure)
You are currently taking, or are expected to take, certain heart or blood pressure medications including long-acting nitrates, soluble guanylate cyclase stimulators, or phosphodiesterase type 5 inhibitors — such as some medications used for chest pain or pulmonary hypertension (confirm with trial site)
You are receiving heart-strengthening medicines given directly into a vein (IV inotropes), or you have a mechanical heart pump device surgically implanted to help your heart

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 5 July 2026

Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: +923448890893

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07444398

Sponsor: Khawaja Danish Ali

Phase: Phase 1

Status: Recruiting

Condition: Heart Disease

Trial contact: +923448890893

More information: https://clinicaltrials.gov/study/NCT07444398

Eligibility summary (AI generated)

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You have been diagnosed with a serious form of heart failure where your heart is not pumping well (specifically, where the heart pumps out 45% or less of its blood with each beat), AND you are experiencing severe breathlessness or fatigue that limits daily activities, or worsening moderate symptoms
Your blood test shows elevated levels of a heart stress marker called NT-proBNP — above 1000 pg/mL if your heart rhythm is normal, or above 1600 pg/mL if you have an irregular heartbeat condition called atrial fibrillation

Who may not be able to join:

Your blood pressure is below 100 mmHg (considered low blood pressure)
You are currently taking, or are expected to take, certain heart or blood pressure medications including long-acting nitrates, soluble guanylate cyclase stimulators, or phosphodiesterase type 5 inhibitors — such as some medications used for chest pain or pulmonary hypertension (confirm with trial site)
You are receiving heart-strengthening medicines given directly into a vein (IV inotropes), or you have a mechanical heart pump device surgically implanted to help your heart

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 5 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 1

Sponsor

Khawaja Danish Ali

Registry

ClinicalTrials.gov

Start date

1 January 2026

Est. completion

31 March 2026

Where this trial is recruiting

🇵🇰 Pakistan

Primary endpoints

Requirement of hospitalization for heart failure; Death from cardiovascular event

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov