Heart Disease Trial, Recruiting NCT07454070 Sponsor: Jing Han Condition: Heart Disease
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Heart Disease Trial, Recruiting

NCT07454070
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have been diagnosed with a serious heart condition called Acute Coronary Syndrome (ACS), such as a heart attack or unstable chest pain
  • It has been between 14 days and 12 months since you had a successful procedure to open a blocked heart artery (called PCI or stenting), and your vital signs are stable
  • You have been diagnosed with depression according to official medical guidelines (DSM-5)
  • Your depression has been assessed as mild-to-moderate using a standard rating scale, and your depression score is higher than your anxiety score (confirm with trial site)
  • You or your legal representative have decided, after being fully informed, not to pursue psychiatric consultation, antidepressant medications, or talking therapies
  • You are willing to take part and have signed a consent form agreeing to join the study

Who may not be able to join:

  • You have severe heart failure that significantly limits your daily activities
  • Your blood pressure is very high and not under control (roughly 180/110 mmHg or above)
  • You have certain abnormal heart rhythm readings on an ECG, a very slow heart rate, or a history of fainting unrelated to your current heart condition (confirm with trial site)
  • You depend on dialysis to filter your blood because your kidneys do not work well enough on their own
  • You have previously had a procedure to cut nerves near the kidney or around the heart (confirm with trial site)
  • Your doctors expect you to survive less than 4 months
  • You were diagnosed before your heart procedure with a serious mental health condition such as schizophrenia, severe intellectual disability, or substance abuse
  • You are currently taking antipsychotic medications
  • You are considered to be at high risk of suicide
  • You are pregnant or currently breastfeeding
  • You have a disease affecting your left ear, a current flare-up of asthma or chronic lung disease, or another condition that would prevent a specific ear-based stimulation treatment used in this trial (confirm with trial site)
  • You have a pacemaker, an implanted heart defibrillator, or any other implanted electrical device such as a vagus nerve or deep brain stimulator

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: wangang Guo, Doctor of Philosophy, Department of Cardiology,Tang-Du Hospital

Phone: 8618506576253

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Jing Han
Registry
ClinicalTrials.gov
Start date
6 January 2026
Est. completion
8 June 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change in depressive symptom severity as measured by the 17-item Hamilton Depression Rating Scale (HAMD-17) from baseline (Week 0) to Week 8

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov