Phase 2 Breast Cancer Trial, Not Yet Recruiting NCT07466303 Sponsor: Xijing Hospital Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Not Yet Recruiting

NCT07466303
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Women between 18 and 70 years of age.
  • People with a confirmed diagnosis of early-stage triple-negative breast cancer (a type of breast cancer that does not respond to certain common hormone-based treatments) who have not yet received any treatment for it.
  • People whose cancer falls within a specific stage range, meaning the tumour and any affected lymph nodes meet certain size and spread criteria as defined by a standard cancer staging system (confirm with trial site).
  • People who have at least one tumour that can be measured on a scan according to standard guidelines.
  • People who are in good enough general health to carry out normal daily activities, with little or no limitation due to illness, as assessed by a standard medical scoring scale.
  • People whose blood counts, liver, kidney, and heart function are within acceptable ranges, as confirmed by tests done within 14 days before joining the trial.
  • People who are willing to provide a tumour tissue sample (either stored from a previous biopsy or freshly taken) for a specific laboratory test.
  • People who are able to understand the trial and are willing to sign a written consent form.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People whose breast cancer has spread to other parts of the body (Stage IV), or who have cancer in both breasts at the time of diagnosis.
  • People who have received any cancer treatment — including chemotherapy, hormone therapy, immunotherapy, or biological therapy — for any cancer within the 4 weeks before the trial treatment would begin.
  • People who have been diagnosed with another cancer in the past 5 years, except for certain treated skin cancers or a specific type of pre-cancerous cervical condition that has been adequately treated.
  • People with a known active HIV infection, active hepatitis B infection (above a certain level), or detectable hepatitis C infection.
  • People who have had an autoimmune disease (where the immune system attacks the body) that required medication to suppress the immune system within the past 2 years.
  • People with serious ongoing health conditions, including active infections requiring antibiotic treatment within the past 2 weeks, certain heart conditions, or a psychiatric condition that could affect the ability to follow the trial requirements.
  • People who have previously received a bone marrow transplant or an organ transplant from another person.
  • Women who are pregnant or breastfeeding, or women who could become pregnant but are unwilling to use a highly effective form of contraception during treatment and for at least 7 months after the last dose.
  • People with a known allergy or sensitivity to any ingredient in the trial medications (serplulimab or SHR-A1811).
  • People who have any other condition that, in the treating doctor's judgement, could affect their safety or their ability to complete the trial.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026

Contact this trial

Phone: 029-84775271

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Sponsor
Xijing Hospital
Registry
ClinicalTrials.gov
Start date
25 March 2026
Est. completion
1 February 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Pathological Complete Response (pCR) Rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov